Results 111 to 120 of about 157,953 (310)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Teamwork and organizational innovation: the moderating role of the HRM context [PDF]

open access: yes, 2014
Evidence is accumulating on the role of teams in shaping a variety of business outcomes, but our knowledge on the effect of teamwork on organizational innovation is still evolving.
Shipton, H.   +17 more
core   +1 more source

The relationship between balanced organizational values and organizational effectiveness: Evidence from business practice

open access: yesEkonomski Vjesnik, 2020
Organizational values are a part of the core ideology of any organization; therefore, managing organizational values is one of the preconditions for achieving business success.
Ivan Malbašić
doaj  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Implications of Global Crisis:Integrate Sustainability with Organizational Culture [PDF]

open access: yes
Sustainability is an issue of escalating importance as a result of structural changes of organizations which are consolidating, downsizing, merging and outsourcing as well as due to the increasing complexity and unpredictability of the external ...
Rao Indu
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Strategic planning effectiveness comparative analysis of the Macedonian context

open access: yesEconomic and Business Review, 2012
Strategic planning is an important element in the organizational success and the key to effectiveness and overall competitiveness of the organizations.
Bobek Šuklev, Stojan Daberliev
doaj  

The Effect of Organizational Learning on Improving Organizational Effectiveness: The Mediating Role of Operational Flexibility

open access: yesمجلة العلوم التربوية والدراسات الإنسانية سلسلة الآداب والعلوم التربوية والإنسانية والتطبيقية
Organizational learning (OL) is a crucial factor in enhancing organizational effectiveness in dynamic and unstable work environments, with particular significance in the healthcare sector.
Rashad Said Dabwaan Al-Makhlaafi   +2 more
doaj   +1 more source

The Effect of Organizational Intelligence on Organizational Learning

open access: yesمطالعات مدیریت بهبود و تحول, 2013
Organizational intelligence is a new concept in organization and management literature. In the information era, the power of mind is superior to physical strength. Despite the dynamic, uncertain and complex operating environments today, benefiting from organizational intelligence and learning process in the organization can increase the competitiveness
Seyed Yaghoub Hosseini   +1 more
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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