Results 121 to 130 of about 965,427 (305)

2008 Annual Performance Report [PDF]

, 2009
Analyzes Irvine's 2008 program impact -- grantmaking, outcomes, and lessons learned and refinement -- and institutional effectiveness -- leadership, constituent feedback, and financial and organizational health.

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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Pengaruh Kepemimpinan dan Kompetensi terhadap Efektivitas Organisasi pada Pegawai Negeri Sipil di Lingkungan Badan Kepegawaian Negara Kantor Regional XII [PDF]

, 2014
Research held in Badan Kepegawaian Negara Kantor Regional XII Pekanbaru. The ai of this study is to analyze the effect of leadership and competency to organizational effectiveness. Samples consist of whole 52 employees of BKN Kantor Regional XII.
Fitri, K. (Kurniawaty), Nasution, Z. (Zulkarnain), Ningsih, D. S. (Dewita)   +2 more
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Investigating the effect of ethical principles of cognitive computing in digital marketing on improving organizational reputation (Case study: B2B businesses) [PDF]

راهبردهای نوآورانه توسعه کسب‌وکارها
Objective: Digital marketing creates an ideal environment for unethical activities, particularly through digital marketing channels that raise privacy concerns among organizations and consumers.
Tahmorath Hasangholipour Yasori, Seyyed Reza Jalalzadeh, Adel Gholamshahi   +2 more
doaj  

Business Intelligence as a Strategic Asset: Enhancing Decision Quality, Effectiveness and Performance in NGOs

Journal of Economy Culture and Society
The exponential growth of unstructured data has prompted organizations to adopt Business Intelligence (BI) tools. While BI adoption in profit-seeking sectors is well-studied, its use in non-governmental organizations (NGOs) remains underexplored.
Meral Dülger Taşkın, Majd Aldin Abou Helal   +1 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Leading for Impact: Exploration of Leadership Styles and Organizational Performance [PDF]

Journal of Emerging Trends in Marketing and Management
Numerous studies have shown that leadership style is a crucial factor in the success and growth of an organization in an environment as volatile as the current one.
Afrim OSMANI, Ledia THOMA
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Navigating works future: Harnessing digital innovation to enhance muslim employees performance through transformation and flexibility

Jema: Jurnal Ilmiah Bidang Akuntansi dan Manajemen
Fierce competition and uneven quality of service have made higher education institutions face pressure to undergo digital transformation and increase human resource performance.
Usep Deden Suherman, Ateng Kusnandar, Husni Rofiq, Suteja Wira Dana Kusuma   +3 more
doaj   +1 more source

MANAGERIAL INVESTMENT ON ORGANIZATIONAL STRESS [PDF]

In a society affected by the economic and financial crisis and in the increasingly competitive environment it is important for any organization to adopt an organizational strategy to reduce costs without affecting its performance and market ...
Iulian Mitut
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