Results 131 to 140 of about 7,718,571 (348)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Strategic planning effectiveness comparative analysis of the Macedonian context

Economic and Business Review, 2012
Strategic planning is an important element in the organizational success and the key to effectiveness and overall competitiveness of the organizations.
Bobek Šuklev, Stojan Daberliev
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

2007 Annual Performance Report [PDF]

, 2008
Based on Irvine's Performance Assessment Framework, reports on program impact -- grantmaking, outcomes, and lessons learned -- and institutional effectiveness -- leadership, constituent feedback, and financial and organizational ...

core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Improving Care for Individuals With Limited English Proficiency: Facilitators and Barriers to Providing Language Services in California Public Hospitals [PDF]

, 2009
Evaluates twelve public hospitals' efforts to improve language services for patients with limited English proficiency: policies and procedures, organizational commitment, strategies for change, training, effectiveness, and facilitators and ...
Alan B. Cohen, Joseph D. Restuccia, Julie Yonek, Romana Hasnain-Wynia   +3 more
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Influence of Human Resource Practices on Internal Customer Satisfaction and Organizational Effectiveness

Acta Universitatis Danubius: Administratio, 2013
It is generally believed that the impact of Human Resource Practices on internal customer satisfaction can create comparative advantage for the organizational performance.
Irfan Ullah, Robina Yasmin
doaj  

Business Intelligence as a Strategic Asset: Enhancing Decision Quality, Effectiveness and Performance in NGOs

Journal of Economy Culture and Society
The exponential growth of unstructured data has prompted organizations to adopt Business Intelligence (BI) tools. While BI adoption in profit-seeking sectors is well-studied, its use in non-governmental organizations (NGOs) remains underexplored.
Meral Dülger Taşkın, Majd Aldin Abou Helal   +1 more
doaj   +1 more source

Impact of Strategic Planning on Organizational Performance and Survival [PDF]

, 2010
The study examined the impact of strategic planning on organizational performance and survival. The effectiveness of strategic planning can be measured in terms of the extent to which it influences organizational performance, which affects its survival ...
Akinyele, S.T., Fasogbon, O.I.
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