Results 201 to 210 of about 1,211,388 (274)

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Fostering organizational performance through innovation: The roles of environmental policy instruments, organizational learning supports, and intellectual capital. [PDF]

Heliyon
Huynh TN, Nguyen PV, Do AM, Dinh PU, Vo HT.   +4 more
europepmc   +1 more source

Unveiling the Role of Cross-Cultural and Cognitive Differences in Organizational Learning Mechanism of Technology-Acquiring Cross-Border Mergers and Acquisitions: Evidence From Emerging Market Enterprises. [PDF]

Front Psychol, 2022
Chen K, Cheng X, Zhang R, Cillo G, Ragusa A.   +4 more
europepmc   +1 more source

Foundation Model‐Enabled Multimodal Deep Learning for Prognostic Prediction in Colorectal Cancer with Incomplete Modalities: A Multi‐Institutional Retrospective Study

Advanced Science, EarlyView.
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu, Chengsheng Zhang, Yingyong Hou, Feng Tang, Weiqi Sheng, Dan Huang, Zhijian Song   +6 more
wiley   +1 more source

Investigating the Impact of Organizational Justice on the Relationship Between Organizational Learning and Organizational Silence in Clinical Nurses: A Structural Equation Modeling Approach. [PDF]

J Nurs Manag
Nemati-Vakilabad R, Mostafazadeh P, Mirzaei A.   +2 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Organizational Learning and Primary Care Nurses' Work Performance and Well-Being: A Multilevel Linear Analysis in a Developing Country. [PDF]

J Nurs Manag
Zhao R, Wang W, Zhang J, Li M, Nicholas S, Maitland E, Yang H, Mitchell R.   +7 more
europepmc   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source

Institution-Wide Retreats Foster Organizational Learning and Action at a Comprehensive Cancer Center. [PDF]

J Cancer Educ
Schrank BR, Fuller JA, Gallagher CM, Morris VK, Holliday EB, Merriman K, Nguyen L, Weaver L, Nelson K, Chiao E, Koong AC, Hawk E, Chang S.   +12 more
europepmc   +1 more source

Will the COVID-19 pandemic transform infection prevention and control in surgery? Seeking leverage points for organizational learning. [PDF]

Int J Qual Health Care, 2021
Toccafondi G, Di Marzo F, Sartelli M, Sujan M, Smyth M, Bowie P, Cardi M, Cardi M.   +7 more
europepmc   +1 more source