Results 241 to 250 of about 7,272,980 (293)

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

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Intranet and Organizational Learning

2006
In this article, we will analyze the cultural dimension of intranets as knowledge management tools within organizations. An intranet is an information communication technology (ICT) based upon Internet technology (http://www, TCP/IP). The intranet phenomenon was introduced in the early 1990s following the idea that it can integrate all the computers ...
Boersma, F.K., Kingma, S.F.
openaire   +2 more sources

Organizational Learning at University

2007
Information and Communication Technologies have transformed the way people work and have an increasing impact on the long life learning. Organizational Learning is an increasingly important area of research that concerns the way organizations learn and thus increase their competitive advantage, innovativeness, and effectiveness.
Marie-Hélène Abel, Dominique Lenne, Adeline Leblanc   +2 more
openaire   +2 more sources

Organizational Structure and Organizational Learning

SSRN Electronic Journal, 2017
In this chapter, we aim to provide a concise overview of the literature on the relationship between organizational structure and organizational learning. The objective is to organize rather than survey the literature in depth, with a view to making opportunities for further research more salient.
Phanish Puranam, Boris Maciejovsky
openaire   +1 more source

The organizational learning curve

European Journal of Operational Research, 2007
Abstract A very practical consequence of organizational learning is that the time required to produce a unit decreases with the total number of units produced. Potentially, this thumb rule known as the learning curve has a great practical importance. Unfortunately, no procedure is available to predict the pace and extent at which the production time
openaire   +2 more sources

The Dynamics of Organizational Learning

SSRN Electronic Journal, 1997
This paper presents a dynamical theory of organizational learning that explicitly accounts for both the introduction of new routines into the manufacturing process i>and improvements in the selection of which procedures to follow. Besides producing a power law of organizational learning with a rate that depends on the effectiveness of the decision ...
openaire   +2 more sources

Organizational Learning and Organizational Improvisation

2018
Organizational learning and organizational improvisation are distinct constructs, but the two processes intertwine in important ways. First, improvisational episodes can lead to long-term group/organizational learning when organizations selectively retain improvised action patterns, or when they learn the process of improvisation itself.
Anne S. Miner, Jay O'Toole
openaire   +1 more source

Organizational Learning

Management Learning, 2000
The burgeoning literature on organizational learning attests to the considerable interest engendered by `organizational learning' and `learning organizations'. At the same time it indicates considerable confusion surrounding these subjects. We discuss four controversial issues regarding organizational learning: (1) What are the similarities and ...
Michael Popper, Raanan Lipshitz
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Organizational Learning

Revista de enfermeria (Barcelona, Spain), 2002
This article presents the reader with conceptual close-up view about the attractive topic organizational apprenticeship and includes and extensive bibliographical file. Therefore, due to the author's effort, we chronologically trace those authors who have contributed to conceptualizing the aforementioned apprenticeship, with particular emphasis on the ...
Marleen Huysman, Dirk de Wit
openaire   +3 more sources