Results 121 to 130 of about 1,200,861 (282)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Silence=Death [poster]

, 1987
full ...
SIlence = Death Project, ACT UP New York
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Misleading Silence

Intro -- Foreword -- Preface -- Table of Contents -- List of Contributors -- List of Cases -- Table of Statutes -- PART I: THEORY AND METHODOLOGY -- 1. Silence and the Regulation of Misleading Conduct: A Taxonomy -- I.
Bant, Elise., Paterson, Jeannie.
core  

Relationship between organizational commitment and organizational silence: A study in the insurance industry

, 2020
In the study, it was aimed to determine the effect of organizational commitment on organizational silence. In this context, the related research was conducted on 416 employees working in an insurance sector company in Istanbul.
Pelin Vardarlıer, Vardarlıer, Pelin, Akıner, Özge, Özge Akıner   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Ethical Climate as a Mediator between Employees' Organizational Silence Behaviors and their Trust in Leader: An Empirical Research on Insurance Sector Employees

, 2018
Leaders play a major role in determining effectiveness across all organizational levels compromising (individual, team and units through their ability of ensuring trust among their subordinates and co-workers).

core  

Investigating the Effect of Organizational Silence and Voice on Employees’ Performance Based on the Mediating Role of Ethical Leadership: A Case Study of Tehran Metropolitan Fire Station

Health in Emergencies & Disasters Quarterly, 2019
Background: The lack of expressing opinions of employees working in organizations can cause a phenomenon called organizational silence. Organizational silence has a damaging effect on employee’s productivity.
Mohammad Mehdi Parhizgar, Matineh Moghaddam, Tohid Alizadeh Hossein Hajlou, Reza Norouzi Ajirloo   +3 more
doaj  

The mediating role of organizational identification in the effect of compulsory citizenship behavior on employee silence: The case of Turkish (Konya province) manufacturing industry

Ekonomski Vjesnik
Purpose: This study discusses the concept of compulsory citizenship behavior (CCB) and identifies the relationships between CCB, organizational identification, and employee silence bearing in mind the Conservation of Resources Theory (COR).
Abdullah Sami Ergül, Gökhan Kerse
doaj   +1 more source