Results 101 to 110 of about 4,887 (259)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Investigating the Effect of Organizational Silence and Voice on Employees’ Performance Based on the Mediating Role of Ethical Leadership: A Case Study of Tehran Metropolitan Fire Station

Health in Emergencies & Disasters Quarterly, 2019
Background: The lack of expressing opinions of employees working in organizations can cause a phenomenon called organizational silence. Organizational silence has a damaging effect on employee’s productivity.
Mohammad Mehdi Parhizgar, Matineh Moghaddam, Tohid Alizadeh Hossein Hajlou, Reza Norouzi Ajirloo   +3 more
doaj  

Organizational Silence: Dimensions, Determinants, and Impact on Management - an Analytical Study

Journal of Vasyl Stefanyk Precarpathian National University
Organizational silence is a significant problem that hinders efficient communication, diminishes employee involvement, and has a detrimental impact on overall organizational performance. This study examines the different aspects of organizational silence,
Mohamed Lamine Slimane Tichtich, Khaiat Amira   +1 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The mediating role of organizational identification in the effect of compulsory citizenship behavior on employee silence: The case of Turkish (Konya province) manufacturing industry

Ekonomski Vjesnik
Purpose: This study discusses the concept of compulsory citizenship behavior (CCB) and identifies the relationships between CCB, organizational identification, and employee silence bearing in mind the Conservation of Resources Theory (COR).
Abdullah Sami Ergül, Gökhan Kerse
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Organizational Silence: Its Devastating Role of Organizational Success

, 2016
Purpose: The purpose of this research is to identify the effects of organizational silence on organizational success at the Egyptian industrial companies in Sadat City. Design/methodology/approach: To assess organizational silence, refer to (organizational silence questionnaire, Schechtman, 2008; Brinsfield, 2009), and organizational success ...
openaire   +2 more sources

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source