Results 81 to 90 of about 4,887 (259)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Journal of Health Management & Informatics, 2017 Introduction: Organizational Culture is one of the most important factors that can change the climate of silence. The main aim of this research was to investigate the influence of organizational culture on employees’ organizational silence in Shiraz ...
Ebrahim Parcham, Alireza Ghasemizad
doaj
Investigating the effect of organizational silence on manpower productivity (Case Study: The main office of Transportation and Terminal Department in central Province) [PDF]
مدیریت بهره وری, 2018 Nowadays, in many organizations, the employees are heard to express their ideas and beliefs concerning the problems in their organizations. This study is dealing with the phenomenon of the organizational silence and its effects on productivity.
Hajieh Rajabi Farjad +2 more
doaj
Journal of Ecophysiology and Occupational Health, 2018 This study aimed to determine effective organizational communication with Organizational Silence and Organizational Citizenship Behavior is done. This research is a quantitative and descriptive survey method. The study population consisted of all employees in the country’s Export Development Bank whose number is 1,200, a sample according to the ...
Samira Taheri +4 more
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Relation between Organizational Silence and burnout among staff nurses [PDF]
Egyptian Journal of Health CareBackground: Organizational silence is a phenomenon that occurs in organizations when employees purposefully withhold information and opinions about the organization, it has joint effect on job performance ratings, and that lead to burnout.
Shrouk Mahdy Shahwan Ali +2 more
doaj +1 more source
The Effect of Psychological Empowerment on Organizational Silence in Hotels
Journal of Business Research - Turk, 2016 The aim of this study is to determine whether psychological empowerment (PE) is related with or have any effects on organizational silence (OS) in hotel enterprises. Relevant data was collected via questionnaire forms from 348 employees of five star hotels operating in Antalya.
Avan, Ali, Zorlu, Özcan, Baytok, Ahmet
openaire +3 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Exploring the Antecedents and Consequences of Organizational Silence in Educational Institutions (Case of Study: Education Organisation in Qom Province) [PDF]
مسائل اجتماعی ایرانOrganizational "silence" represents a critical challenge within educational institutions, obstructing the optimal utilization of employees' knowledge and experiences.
Ali Heydari Qomi +2 more
doaj