Results 81 to 90 of about 145,435 (260)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Paths to positivity: exploring the dynamics of positive organizing [PDF]
This paper advances a theory about the way patterns of positive and negative organizing unfold. It is grounded in data collected from 58 individuals.
Cunha, Miguel Pina e +2 more
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
INTERNAL DEMARKETING: CONSTRUCT, RESEARCH PROPOSITIONS AND MANAGERIAL IMPLICATIONS [PDF]
To a large degree, organizations strive for marketing and selling themselves as good employers. However, by a wide range of actions, practices, mistakes, and premises they can most notably demotivate rather than motivate their workforces.
Anselmo Ferreira VASCONCELOS
core
Fostering Organizational Learning: The Impact of Work Design on Workarounds, Errors, and Speaking Up about Internal Supply Chain Problems [PDF]
, 2012 A potential avenue for organizational learning is frontline employees’ experience with internal supply chain problems. However, extensive research has established that employees rarely speak up to managers about problems.
Tucker, Anita Lynn
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
ORGANIZATIONAL SILENCE IN WHITE-COLLAR WORKERS: A RESEARCH ON BANK BRANCH EMPLOYEES
Sakarya Üniversitesi İktisat Dergisi, 2017 The purpose of this researchis to examine the factors that create the organizational silence climate overoccupational silence, and the effects of employee silence behavior on jobsatisfaction, organizational commitment and burnout.For the research ...
Bülent Turan, Gürkan Haşit
doaj
Ekonomski VjesnikPurpose: This study discusses the concept of compulsory citizenship behavior (CCB) and identifies the relationships between CCB, organizational identification, and employee silence bearing in mind the Conservation of Resources Theory (COR).
Abdullah Sami Ergül, Gökhan Kerse
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source