Results 91 to 100 of about 6,721 (293)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The Role of Leadership and Organizational Culture in Influencing Employee Silence: A Systematic Review of the Evidence.

, 2020
Employee silence is a silent killer of organizations, stripping them of lost revenue, productivity, and divergent thought. If organizations wish to reduce employee silence behaviors, they need to understand the factors in their organizational culture and
Flanagan-Benedict, Geneva
core  

ORGANIZATIONAL SILENCE: SUATU PENGHAMBAT DALAM MEWUJUDKAN KREATIFITAS ORGANISASIONAL

, 2016
There are powerful forces in many organzations that cause widespread withholding of information about potential problems or issues by employess, this collective-level phenomenon as ‘organizational silence’.
Retnawati, Berta Bekti
core   +1 more source

Influence of Head Nurses' Abusive Supervision on Nurses' Organizational Silence: A Descriptive-correlation Study [PDF]

Tanta Scientific Nursing Journal
Abusive supervision is a logical factor that promotes nurses to display negativefeelings, depletes their cognitive resources, and diminishes their perspectives ofinteractional justice and silent behaviors. Aim: Assess the influence of head nurses'abusive
Maha Shukair, Samer Shehata, Reda Abo Gad, Sara Mostaf   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Employees’ Expectation and Organizational Silence

Annals of Dunarea de Jos University of Galati. Fascicle I. Economics and Applied Informatics, 2019
The study investigated the relationship between employees’ expectation (EE) and organizational silence (OS). Design/Methodology: A survey of one hundred and eight (108) working class Professional Master Students was carried out eliciting responses through a self- constructed instrument that has Cronbach alpha of 0.864 and 0.825 reliability values for ...
openaire   +2 more sources

Assessment of Effective Organizational Communication on Organizational Silence and Organizational Citizenship Behavior

Journal of Ecophysiology and Occupational Health, 2018
This study aimed to determine effective organizational communication with Organizational Silence and Organizational Citizenship Behavior is done. This research is a quantitative and descriptive survey method. The study population consisted of all employees in the country’s Export Development Bank whose number is 1,200, a sample according to the ...
Samira Taheri, Parya Amirhasani, Reza Moradi, Esmail Ghaderi, Mohammad Ali Manafzadeh   +4 more
openaire   +2 more sources

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

PENGARUH ORGANIZATIONAL SILENCE TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR PADA TENAGA KESEHATAN [PDF]

Penelitian ini bertujuan untuk mengetahui apakah terdapat pengaruh dari setiap dimensi organizational silence terhadap organizational citizenship behavior (OCB) pada tenaga kesehatan. Metode penelitian ini yaitu kuantitatif.
PUTRI NATASYA NASUTION, .
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source