Results 91 to 100 of about 1,995,364 (294)

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

When is Trust Produced and When Does it Matter? Taking a Closer Look at Trust and Alliance Performance. [PDF]

open access: yes
In response to intense competition in the environment and rapid technological shifts, firms have increasingly turned to alternative organizational forms such as strategic alliances.
Krishnan, R.
core  

The Effects of Employee’s Perceptions of Organizational Justice and Organizational Trust on Organizational Commitment: A Research on a Public Organization

open access: yesGaziantep Üniversitesi Sosyal Bilimler Dergisi, 2014
In this study, it is aimed to present the senses of employees about organizational justice, organizational trust and organizational commitment; and also to research the effects of organizational justice and organizational trust perceptions on ...
Hakan CANDAN
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Trust in electronic banking [PDF]

open access: yes, 2014
Trust among stakeholders is vital for the successful implementation of IS projects such as electronic banking, because such IS initiative do not typically require face-to-face interactions.
David-West, O, Abubakre, M
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Organizational Trust and Organizational Identification: As Mediator of The Relationship between Procedural Justice and Employee Engagement [PDF]

open access: yes, 2016
Employee engagement in the workplace is very important, especially for the organizational competitive advantage. Workplace procedural justice is an important motivator for employee work attitude and performance.
Praptini Yulianti
core   +2 more sources

Organizational Trust Levels of Elementary Teachers: A Qualitative Study

open access: yesGaziantep Üniversitesi Sosyal Bilimler Dergisi, 2013
Today, the main feature of a well-functioning organization is trust in the organization. In the research, it is researched which conceptions are needed to ensue organizational trust by the teachers who work in the primary schools and that the effects of ...
Mukadder BOYDAK ÖZAN   +1 more
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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