Results 81 to 90 of about 66,056 (262)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The Effectiveness of job Rotation and it's Relationship with Organizational Justice and Organizational Trust [PDF]

پژوهش‌های مدیریت عمومی, 2014
The purpose of this research is studying the Effectiveness of job rotation and it's relationship with organizational justice and organizational trust among the nurses Of social security hospital of Zahedan.statistical society of this research includes ...
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Demographic Variables and Their Impact on Organizational Trust

Future Human Image
This study explores the impact of demographic variables on organizational trust. It aims to present the concept of organizational trust and its dimensions, addressing its determinants, both personal and organizational.
Amira Khaiat, Mohammed Lamine Slimane Tichtich   +1 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Organizational trust, usability, and inclusivity are key implementation facilitators for a proposed assets-based mobile health intervention. [PDF]

Transl Behav Med, 2023
White MJ, Xie R, Lane H, Rodriguez J, Gilchrist L, Howard J, Perrin EM, Skinner A, Silberberg M.   +8 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

When Chinese Employees Speak Up: The Experience of Organizational Trust and Authenticity Enhances Employees' Voice Behavior. [PDF]

Int J Environ Res Public Health, 2022
Liu X, Song L, Zheng J, Wang Y.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

An examination of the relationships between organizational support, trust, identification, and commitment among disabled healthcare workers employed in public hospitals in Turkey

Discover Public Health
Objective Disabled healthcare workers represent an underrepresented segment of the health workforce and may experience organizational life differently because of structural and psychosocial barriers.
Ulku Turkugur, Mevlut Karadag, Ismet Sahin, Bayram Sahin   +3 more
doaj   +1 more source