Results 51 to 60 of about 63,731 (192)
Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B) [PDF]
, 2013 Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and ...
Nag, Sangram
core +1 more source
Beilstein Journal of Organic Chemistry, 2013 The trifluoromethylation of aryl iodides catalyzed by copper(I) salt with trifluoromethylzinc reagent prepared in situ from trifluoromethyl iodide and Zn dust was accomplished.
Yuzo Nakamura +6 more
doaj +1 more source
Organo-Fluorine Compounds as Artificial Blood Substitute
Defence Science Journal, 1980 The rate of fluoro-carbon compounds as artificial substitute for blood has been discussed. Blood is a complicated body fluid. At first glance it seems impossible that such a complicated body fluid can be replaced by artificial synthesized fluids or any substitute for this can be synthesized.
openaire +1 more source
The influence of fluorine substitution on some enzyme mediated reactions [PDF]
, 1997 The replacement of a hydrogen or hydroxy group with a fluorine atom is a popular strategy to alter the activity of biologically important molecules, as their similar sizes mean that such a replacement has little steric impact.
Bridge, Colin Francis
core
Oxidative 3,3,3-trifluoropropylation of arylaldehydes
Beilstein Journal of Organic Chemistry, 2013 A reaction between (E)-trimethyl(3,3,3-trifluoroprop-1-en-1-yl)silane (1) and arylaldehydes 2 was triggered by fluoride anions to afford aryl 3,3,3-trifluoropropyl ketones 3 in moderate to good yield.
Akari Ikeda +6 more
doaj +1 more source
Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis
ChemistryOpen, Volume 15, Issue 6, June 2026.This review highlights synthetic advances (2013–2025) in intramolecular C─N bond formation for constructing the pharmaceutically relevant pyrrolidine core. The review is organized into five methodological clusters: 1) intramolecular alkene/alkyne amination; 2) tandem annulations, which involve C─N bond formation as the key step; 3) nucleophilic ...
Rasma Kroņkalne, Māris Turks
wiley +1 more source
Chemical diffusion of fluorine in jadeite melt at high pressure [PDF]
, 1984 The chemical diffusion of fluorine in jadeite melt has been investigated from 10 to 15 kbars and 1200 to 1400°C using diffusion couples of Jadeite melt and fluorine-bearing jadeite melt (6.3 wt.% F). The diffusion profile data indicate that the diffusion
Scarfe, Christopher M. +1 more
core +1 more source
Prins fluorination cyclisations: Preparation of 4-fluoro-pyran and -piperidine heterocycles
Beilstein Journal of Organic Chemistry, 2010 The Prins reaction was investigated using BF3·OEt2 as a Lewis acid. It has been recently demonstrated, that if BF3·OEt2 is used in stoichiometric amounts then these reactions generate fluorinated products where the BF3·OEt2 contributes fluoride ion to ...
Guillaume G. Launay +2 more
doaj +1 more source
A Direct Method to Prepare Zwitterionic Organotrifluoroborates: Ammonium and Sulfonium Derivatives
European Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.Organotrifluoroborates find applications in synthesis, diagnostics, and theranostics. This study outlines a one‐step reaction for producing ammonium and sulfonium trifluoroborate zwitterion derivatives. This method achieves satisfactory yields without the need for expensive reagents.
Vanessa Re +6 more
wiley +1 more source
Fluorine polymer probes for magnetic resonance imaging: quo vadis?
, 2019 Over the last few years, the development and relevance of F-19 magnetic resonance imaging (MRI) for use in clinical practice has emerged. MRI using fluorinated probes enables the achievement of a specific signal with high contrast in MRI images. However,
Babuka, David +4 more
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