Results 51 to 60 of about 2,457 (204)

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Asymmetric Synthesis of Tertiary α -Hydroxyketones by Enantioselective Decarboxylative Chlorination and Subsequent Nucleophilic Substitution

Molecules, 2020
Chiral tertiary α-hydroxyketones were synthesized with high enantiopurity by asymmetric decarboxylative chlorination and subsequent nucleophilic substitution.
Mei Kee Kam, Akira Sugiyama, Ryouta Kawanishi, Kazutaka Shibatomi   +3 more
doaj   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Trigonal Phosphine Umpolung: Electrophilicity Driven by a Redox‐Active Boron Cluster

Chemistry – A European Journal, EarlyView.
Coupling of a phosphine to a redox‐active cluster enables polarity reversal, or umpolung, at phosphorus. Phosphines are classically known for their nucleophilicity, and while electrophilic reactivity has been observed in geometrically constrained, non‐trigonal systems, similar behavior in ordinary trigonal phosphines is rare.
Bryce C. Nussbaum, Mark D. Smith, Dmitry V. Peryshkov   +2 more
wiley   +1 more source

Stereoselective Higher‐Order [10+4]‐ and [10+6] Cycloadditions Between Two Highly Unsaturated and Ambiphilic π‐Addends

Chemistry – A European Journal, EarlyView.
Aminocatalytically generated isobenzofulvenes and 3‐oxidopyridinium betaines act as ambiphilic reaction partners in orbital‐symmetry‐allowed [10+4] cycloadditions or formally symmetry‐forbidden concerted thermal [10+6] cycloadditions. The reaction furnishes three cycloadducts: one [10+4] cycloadduct and two regioisomeric [10+6] cycloadducts.
Jonas Faghtmann, Anne Kristensen, Fabien Fritz, Signe Sofie Pladsbjerg Andresen, Anne Rask Østergaard, Johannes Nygaard Lamhauge, K. N. Houk, Karl Anker Jørgensen   +7 more
wiley   +1 more source

Organocatalyst-mediated five-pot synthesis of (–)-quinine

Nature Communications, 2022
Syntheses of quinine have fascinated organic chemists for over a hundred years. Here, the authors developed an organocatalyst-mediated pot-economical enantioselective total synthesis using five reaction vessels.
Takahiro Terunuma, Yujiro Hayashi
doaj   +1 more source

N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions

Chemistry – A European Journal, EarlyView.
Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero, Gaetano D'Onghia, Federica Fina, Zakaria Ziani, Luca Sensoli, Andrea Gualandi, Andrea Fermi, Paola Ceroni, Pier Giorgio Cozzi   +8 more
wiley   +1 more source

Robust perfluorophenylboronic acid-catalyzed stereoselective synthesis of 2,3-unsaturated O-, C-, N- and S-linked glycosides

Beilstein Journal of Organic Chemistry, 2019
A convenient protocol was developed for the synthesis of 2,3-unsaturated C-, O-, N- and S-linked glycosides (enosides) using 20 mol % perflurophenylboronic acid catalyst via Ferrier rearrangement.
Madhu Babu Tatina, Xia Mengxin, Rao Peilin, Zaher M. A. Judeh   +3 more
doaj   +1 more source

A Fluorescent and Switchable Rotaxane Dual Organocatalyst [PDF]

Organic Letters, 2016
Rotaxane organocatalysis presents a new direction toward controlled one-pot catalytic reactions. By combining molecular switches and catalysts, fluorescence and pH-responsive switching along with the exclusive selectivity of dual catalytic reactions are demonstrated.
Chak-Shing, Kwan, Albert S C, Chan, Ken Cham-Fai, Leung   +2 more
openaire   +3 more sources

Flipping the Card With Enantiodivergent Organocatalysis

Chemistry – A European Journal, EarlyView.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre, Alessio Carioscia, Alessandro Brusa, Armando Carlone   +3 more
wiley   +1 more source