Results 51 to 60 of about 6,365 (202)

Conformational Analysis and Organocatalytic Activity of Helical Stapled Peptides Containing α-Carbocyclic α,α-Disubstituted α-Amino Acids

Molecules
Conformational freedom-restricted peptides, such as stapled peptides, play a crucial role in the advancement of functional peptide development. We synthesized stapled octapeptides using α-carbocyclic α,α-disubstituted α-amino acids, particularly 3 ...
Akihiro Iyoshi, Atsushi Ueda, Tomohiro Umeno, Takuma Kato, Kazuhiro Hirayama, Mitsunobu Doi, Masakazu Tanaka   +6 more
doaj   +1 more source

Recent applications of chiral calixarenes in asymmetric catalysis

Beilstein Journal of Organic Chemistry, 2018
The use of calixarenes in asymmetric catalysis is receiving increasing attention due to their tunable three-dimensional molecular platforms along with their easy syntheses and versatile modification at the upper and lower rims. This review summarizes the
Mustafa Durmaz, Erkan Halay, Selahattin Bozkurt   +2 more
doaj   +1 more source

Asymmetric Synthesis of Tertiary α -Hydroxyketones by Enantioselective Decarboxylative Chlorination and Subsequent Nucleophilic Substitution

Molecules, 2020
Chiral tertiary α-hydroxyketones were synthesized with high enantiopurity by asymmetric decarboxylative chlorination and subsequent nucleophilic substitution.
Mei Kee Kam, Akira Sugiyama, Ryouta Kawanishi, Kazutaka Shibatomi   +3 more
doaj   +1 more source

Introduction of abnormal N-heterocyclic carbene as an efficient organocatalyst: ring opening polymerization of cyclic esters

, 2011
The recently isolated abnormal N-heterocyclic carbene (aNHC) has been established as an efficient organocatalyst in ring opening polymerization of three different cyclic estersrac-lactide (rac-LA), ε-caprolactone (ε-CL), and δ-valerolactone (δ-VL ...
Samaresh Ch. Sau, Swadhin K. Mandal, Debasis Koley, Sen, Tamal K., Arghya Modak, Mandal, Swadhin K., Koley, Debasis, Arup Mukherjee, Sau, Samaresh Ch., Modak, Arghya, Tamal K. Sen, Mukherjee, Arup   +11 more
core   +1 more source

Enantioselective synthesis of dihydroquinazolinone derivatives catalyzed by a chiral organocatalyst

, 2017
The asymmetric condensation/amine addition cascade reaction catalysed by a effective chiral organocatalyst for the formation of 2,3-dihydroquinazolinones with high yields (up to 99%) and ee's (up to 97%).
Veeramanoharan Ashokkumar, Ponmuthu Kottala Vijaya, Chithiraikumar Chinnadurai, Sepperumal Murugesan, Sankar Balakrishnan, Siva Ayyanar, Madhappan Mariyappan, Velu Sadhasivam   +7 more
core   +1 more source

Synthesis and Crystal Structure of 1-(3-fluorophenyl)-3-(3,4,5-trimethoxybenzoyl)thiourea [PDF]

, 2011
The title thiourea was synthesized by reaction of 3,4,5-trimethoxybenzoyl isothiocyante with 3-fluoroaniline. The 3,4,5-trimethoxybenzoyl isothiocyante was produced in situ by reaction of 3,4,5-trimethoxybenzoyl chloride with ammonium thiocyanate in dry ...
Bolte, Michael, Michael Bolte, Shaheen, Uzma, Uzma Shaheen, Saeed, Aamer, Aamer Saeed   +5 more
core   +1 more source

A Recyclable Chiral 2-(Triphenylmethyl)pyrrolidine Organocatalyst Anchored to [60]Fullerene

, 2019
Hybridization of a chiral 3-hydroxy-2-trityl-pyrrolidine deriving from (R)-pyrrolidinol with [60] fullerene via click chemistry provides a highly efficient supported enantioselective organocatalyst, which was successfully exploited in a Michael ...
MARTINELLI, ADA, Rosso C., Lombardo M., Martinelli A., Trombini C., Prato M., Emma M. G., EMMA, MARCO GIUSEPPE, Quintavalla A., Syrgiannis Z.   +9 more
core   +1 more source

Robust perfluorophenylboronic acid-catalyzed stereoselective synthesis of 2,3-unsaturated O-, C-, N- and S-linked glycosides

Beilstein Journal of Organic Chemistry, 2019
A convenient protocol was developed for the synthesis of 2,3-unsaturated C-, O-, N- and S-linked glycosides (enosides) using 20 mol % perflurophenylboronic acid catalyst via Ferrier rearrangement.
Madhu Babu Tatina, Xia Mengxin, Rao Peilin, Zaher M. A. Judeh   +3 more
doaj   +1 more source

Organocatalyst-mediated five-pot synthesis of (–)-quinine

Nature Communications, 2022
Syntheses of quinine have fascinated organic chemists for over a hundred years. Here, the authors developed an organocatalyst-mediated pot-economical enantioselective total synthesis using five reaction vessels.
Takahiro Terunuma, Yujiro Hayashi
doaj   +1 more source

Methyl 12-D-prolinoylaminocholate as a versatile organocatalyst for the asymmetric aldol reaction of cyclic ketones

, 2007
The use of cholic acid derivative 1, bearing a D-prolinamide moiety linked at the 12-position of cholic acid methylester, as an organocatalyst in the asymmetric aldol reaction of cyclic ketones and aromatic aldehydes, gave the corresponding aldol ...
IULIANO, ANNA, PULEO G. L
core   +1 more source