Results 121 to 130 of about 72,062 (325)
Journal of NeuroEngineering and Rehabilitation, 2018 Background Friedreich ataxia (FRDA) is a disease with neurological and systemic involvement. Clinical assessment tools commonly used for FRDA become less effective in evaluating decay in patients with advanced FRDA, particularly when they are in a ...
Bruno Bonnechère +6 more
doaj +1 more source
Image-based Parameter Inference for Spatio-temporal models of Organogenesis [PDF]
arXiv, 2014 Advances in imaging technology now provide us with detailed 3D data on gene expression patterns in developing embryos. This information can be used to build predictive mathematical models of embryogenesis. Current modelling approaches are, however, limited by lack of methods to automatically infer the regulatory networks and the parameter values from ...
arxiv
Comprehensive Review of the Impact of Maternal Stress on Fetal Development
Pediatric Discovery, EarlyView.ABSTRACT Maternal stress impacts millions of pregnant women across the globe each year and refers to mental or psychological stress that occurs during the prenatal period. Although it remains known that maternal stress can negatively impact maternal health, the downstream effects of stress on fetal and infant development in the long‐term are unclear ...
Divya Tadanki +8 more
wiley +1 more source
Sensors, 2018 Optoelectronic devices are the gold standard for 3D evaluation in clinics, but due to the complexity of this kind of hardware and the lack of access for patients, affordable, transportable, and easy-to-use systems must be developed to be largely used in ...
Bruno Bonnechère +4 more
doaj +1 more source
Three-dimensional cell culture model for hepatocytes opens a new avenue of real world research on liver [PDF]
arXiv, 2019 3-demensional (3D) culture model is a valuable in vitro tool to study liver biology, metabolism, organogenesis, tissue morphology, drug discovery and cell-based assays. Compelling evidence suggests that cells cultured in 3D model exhibit superior liver-specific functions over the conventional 2-dimentional (2D) culture in evaluating hepatobiliary drug ...
arxiv
Small Methods, EarlyView.Mechanical strain influences tissue development, homeostasis, and disease. The TissueTractor, a high‐strain stretcher system, enables high‐resolution imaging of live tissues and cells under strain, revealing cellular strain heterogeneity, cytoskeletal remodeling, and morphological adaptations in various model systems.
Jing Yang +11 more
wiley +1 more source
Aging Cell, EarlyView.Larvae derived from a cross between tert deficient and haploinsufficient fish show a premature aging phenotype, characterized by telomere attrition and early death. The ST2 larval model is a valuable tool for rapid screening of antiaging molecules. Given that organogenesis occurs within the first 48 h, this model also allows for the conduction of aging
David Hernández‐Silva +5 more
wiley +1 more source
Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells
Nature Communications, 2016 It is difficult to generate functional human anterior pituitary tissues in vitro. Here, Ozone et al. generate human anterior pituitary from embryonic stem cells by recapitulating in vivodevelopment, and demonstrate this tissue secretes hormones and ...
Chikafumi Ozone +8 more
doaj +1 more source
A morphogenetic crop model for sugar-beet (Beta vulgaris L.) [PDF]
ISCMDS (2008), 2008 This paper is the instructions for the proceeding of the International Symposium on Crop. Sugar beet crop models have rarely taken into account the morphogenetic process generating plant architecture despite the fact that plant architectural plasticity plays a key role during growth, especially under stress conditions. The objective of this paper is to
arxiv
Impact of Metabolic Surgery on Gestational Diabetes Mellitus: A Cohort Analysis
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT Background With the upsurge of obesity in Australia and worldwide, the incidence of metabolic surgery is increasing in women of reproductive age. Metabolic surgery reduces the rate of gestational diabetes mellitus, however, the risk remains about that for the general population.
Jasmine Wintour +4 more
wiley +1 more source