Results 141 to 150 of about 91,856 (332)

Dynamics of Size and Shape Variation During Embryonic Development in the Balkan Crested Newt

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Morphological variance in Triturus ivanbureschi embryos fluctuates during the tailbud phase, coinciding with developmental arrest caused by the balanced lethal system. Prehatching embryos show uniform variance. Our study reveals dynamics of morphological variability during early development and provides a baseline for further studies.
Marko Bugarčić, Ana Ivanović, Milena Cvijanović, Maja Ajduković, Marija Drobnjaković, Ben Wielstra, Tijana Vučić   +6 more
wiley   +1 more source

Contribution of epithelial-mesenchymal transitions to organogenesis and cancer metastasis

Current Opinion in Cell Biology, 2018
The epithelial-to-mesenchymal transition (EMT) plays crucial roles during development, and inappropriate activation of EMTs are associated with tumor progression and promoting metastasis.
Kyra Campbell
semanticscholar   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Optimized Individualized Nursing Improves Recovery and Reduces Complications in ICU Patients with Severe Pneumonia

Organogenesis
Objective This study evaluates the effectiveness of optimized individualized nursing interventions on clinical outcomes in intensive care unit (ICU) patients with severe pneumoniaMethods In this randomized controlled trial, 76 patients with severe ...
Linjuan Wu, Jingchuan Lin
doaj   +1 more source

AGRN‐, LRP4‐, MUSK‐Related CMS: Clinical, Neurophysiological, Morphological, Genetic and Pathological Mechanisms

Muscle &Nerve, EarlyView.
ABSTRACT Congenital myasthenic syndromes (CMS) are inherited disorders caused by mutations in genes encoding proteins essential for neuromuscular junction (NMJ) function. Pathogenic variants have been identified in more than 35 genes, underscoring the complexity of synaptic biology and the wide range of mechanisms that can compromise neuromuscular ...
Rocio‐Nur Villar‐Quiles, Damien Sternberg, Marie‐Christine Nougues, Arnaud Isapof, Bruno Eymard, Stéphanie Bauché   +5 more
wiley   +1 more source

SS-31 Targets NOS2 to Enhance Osteogenic Differentiation in Aged BMSCs by Restoring Mitochondrial Function

Organogenesis
This study delves into the rejuvenating effects of SS-31 on aged human Bone Marrow-Derived Mesenchymal Stem Cells (BM-MSCs), focusing on its potential to restore their diminished osteogenic differentiation capacity, a critical issue in geriatric medicine
Sen Duan, Qindong Zhang, Jinqiang Zhu, Jiaming Wang   +3 more
doaj   +1 more source

An Apo-14 promoter-driven transgenic zebrafish that marks liver organogenesis.

, 2011
Several transgenic zebrafish lines for liver development studies had been obtained in the first decade of this century, but not any transgenic GFP zebrafish lines that mark the through liver development and organogenesis were reported.
Gui Jian-Fang, Li, Zhi, Jian-Fang Gui, Gui, Jian-Fang, Rui Wang, Wang, Rui, Wang Yang, Wang, Yang, Wang, R (reprint author), Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan, Peoples R China, jfgui@ihb.ac.cn, Wang Rui, Yang Wang, Zhi Li, Li Zhi   +13 more
core   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Calcium Imaging in Vivo: How to Correctly Select and Apply Fiber Optic Photometric Indicators

Organogenesis
Fiber-photometric is a novel optogenetic method for recording neural activity in vivo, which allows the use of calcium indicators to observe and study the relationship between neural activity and behavior in free-ranging animals.
Lanxia Wu, Wenxuan Sun, Linjie Huang, Lin Sun, Jinhua Dou, Guohua Lu   +5 more
doaj   +1 more source

Benzimidazole Anthelmintic Compounds Albendazole and Fenbendazole Show Distinct Toxicity on the Nitrogen Fixing Bacterium Mesorhizobium loti and Its Symbiosis With Lotus japonicus

Environmental Toxicology, EarlyView.
ABSTRACT Veterinary medicines, which reach the soil mostly through the application of contaminated manures, can affect beneficial soil microorganisms, such as nitrogen‐fixing rhizobia bacteria, which engage in important symbiotic associations with plants.
Polyxeni Gorgia, Stathis Lagos, Christina N. Nikolaou, Nikoleta Basdeki, Christos Papadopoulos, Dimitrios G. Karpouzas, Daniela Tsikou   +6 more
wiley   +1 more source