Results 161 to 170 of about 69,048 (266)
Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9, PKD1L1, MMP21, and GDF1
Integrating trio‐based genomic sequencing with detailed clinical evaluation across seven French–Vietnamese heterotaxy cases alongside a review of 108 published patients reveals strong genotype–phenotype correlations. Variants in DNAH9, PKD1L1, MMP21, and GDF1 define a broad spectrum from isolated situs inversus to complex conotruncal heart defects and ...
Thi Bich Tuyen Ho +23 more
wiley +1 more source
Branching out or bearing fruit: how MADS-box transcription factors orchestrate maize ovule development. [PDF]
Prakash V.
europepmc +1 more source
In the Drosophila ovarian niche, an E‐cadherin‐to‐N‐cadherin switch, mediated by Wnt‐mir‐994 signalling, is repurposed to ensure niche resilience. This compensatory mechanism maintains niche integrity and stem cell support upon E‐cadherin loss, revealing a robustness circuit.
Renjun Tu +6 more
wiley +1 more source
Liver Organoids: From Disease Modelling to Regenerative Medicine
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang +5 more
wiley +1 more source
Human-Mouse Chimerism for Organogenesis Without Neural or Germline Contributions. [PDF]
Ye S +7 more
europepmc +1 more source
Abstract Objective This study was conducted to describe pregnancy outcomes reported following maternal or paternal exposure to galcanezumab in clinical trials and postmarketing surveillance. Background Galcanezumab is a calcitonin gene‐related peptide‐inhibiting monoclonal antibody indicated for the preventive treatment of migraine.
Irene Boz +8 more
wiley +1 more source
Bringing human early embryo development to clinical interpretation: HESTA as an evolving reference. [PDF]
Li Y +6 more
europepmc +1 more source
ABSTRACT Bronchopulmonary dysplasia (BPD) is a heterogeneous developmental lung disorder resulting from the interaction between antenatal susceptibility and postnatal injury. Increasing evidence suggests that its biological origins may precede preterm birth, with placental dysfunction, fetal growth restriction, inflammation and oxidative stress ...
Serafina Perrone +13 more
wiley +1 more source
Curcumin-rich plant material production through a robust and reproducible micropropagation protocol. [PDF]
Cacaï GHT +5 more
europepmc +1 more source
Auxin response and PIN‐mediated transport in chlorophyte algae
Like multicellular plants, green algae respond to auxin and move it across their cells. However, their PIN‐like proteins do not act like plant auxin exporters, suggesting that basic auxin transport evolved early and specialized directional transport appeared later in plant evolution.
Adrijana Smoljan +11 more
wiley +1 more source

