The C. elegans tailless/Tlx homolog nhr-67 regulates a stage-specific program of linker cell migration in male gonadogenesis [PDF]
Cell migration is a common event during organogenesis, yet little is known about how migration is temporally coordinated with organ development. We are investigating stage-specific programs of cell migration using the linker cell (LC), a migratory cell ...
Abraham +61 more
core +3 more sources
Modeling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary
Organogenesis is a complex and interconnected process that is orchestrated by multiple boundary tissue interactions1–7. However, it remains unclear how individual, neighbouring components coordinate to establish an integral multi-organ structure. Here we
H. Koike +11 more
semanticscholar +1 more source
mRNA methylation at the N6-position of adenosine (m6A) enables multiple layers of post-transcriptional gene control, often via RNA-binding proteins that use a YT521-B homology (YTH) domain for specific m6A recognition.
Laura Arribas‐Hernández +7 more
semanticscholar +1 more source
A Model for the Development of the Rhizobial and Arbuscular Mycorrhizal Symbioses in Legumes and Its Use to Understand the Roles of Ethylene in the Establishment of these two Symbioses [PDF]
We propose a model depicting the development of nodulation and arbuscular mycorrhizae. Both processes are dissected into many steps, using Pisum sativum L. nodulation mutants as a guideline. For nodulation, we distinguish two main developmental programs,
Albrecht C. +192 more
core +2 more sources
Hard-to-heal wounds can be detrimental to patients’ quality of life. Currently, there is scarcity of therapeutic alternatives to mainstay surgical treatment, which uses the principles of tissue debridement, temporary wound coverage, and subsequent tissue
Hadjipanayi Ektoras +5 more
doaj +1 more source
Lineage dynamics of murine pancreatic development at single-cell resolution. [PDF]
Organogenesis requires the complex interactions of multiple cell lineages that coordinate their expansion, differentiation, and maturation over time.
Byrnes, Lauren E +8 more
core +2 more sources
Organogenesis and plant regeneration of Arachis villosa Benth. (Leguminosae) through leaf culture [PDF]
With the aim of developing an efficient plant regeneration protocol, leaflet explants of three accessions of Arachis villosa Benth. (S2866, S2867 and L97) were cultured on basic Murashige and Skoog medium supplemented with different combinations of plant
Fontana, María Laura +2 more
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Hepatocytes play important roles in the liver, but in culture, they immediately lose function and dedifferentiate into progenitor-like cells. Although this unique feature is well-known, the dynamics and mechanisms of hepatocyte dedifferentiation and the ...
Shizuka Miura +9 more
doaj +1 more source
Simulating Organogenesis in COMSOL: Comparison Of Methods For Simulating Branching Morphogenesis
During organogenesis tissue grows and deforms. The growth processes are controlled by diffusible proteins, so-called morphogens. Many different patterning mechanisms have been proposed.
Aland, Sebastian +3 more
core +1 more source

