Results 71 to 80 of about 44,882 (183)

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche, Namdev More, Tiffany Lee, Mia Orr, Anne Camus, Devina Purmessur, Sarah E. Gulbrand, Nadeen O. Chahine, Lara Silverman, Dmitriy Sheyn   +9 more
wiley   +1 more source

Hormone-modulated transcription factors orchestrating the root nodule symbiosis. [PDF]

Front Plant Sci
Kirolinko C, Yacullo M, Blanco F, Zanetti ME.   +3 more
europepmc   +1 more source

Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants

Clinical Genetics, Volume 110, Issue 3, Page 325-335, September 2026.
SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel, Xiaonan Zhao, Nichole M. Owen, Tia Gordon, Mahshid S. Azamian, Eric C. Kao, Fan Xia, Xi Luo, Jill A. Rosenfeld, Seema R. Lalani, Allison P. Ortega, Steven B. Bleyl, Florence Petit, Sulekha Rajagopolan, Bénédicte Demeer, Meredith K. Gillespie, Lijia Huang, Matthew Osmond, Kym M. Boycott, Kyra E. Stuurman, Marjon A. van Slegtenhorst, Haley Soller, Céline Jost, Aurore Garde, Hana Safraou, Laurence Faivre, Victor Faundes, Daryl A. Scott   +27 more
wiley   +1 more source

Computational identification of lineage-committed precursors in mammalian organogenesis reveals a novel hematopoietic enhancer regulating Bhlhe41 expression. [PDF]

Brief Bioinform
Jin L, Han Z, Hannah R, Shao H, Huang J, Wang S, Zhang W, Lin J, Sun K, Yu Y.   +9 more
europepmc   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

Establishment of an Organogenesis-Based Regeneration System and Induction of Somatic Embryogenesis in <i>Catalpa ovata</i>. [PDF]

Plants (Basel)
Bao P, Huo X, Sun J, Qu G, Ma W, Wang J, Hu R.   +6 more
europepmc   +1 more source

Pangenome and Pan‐Transcriptome Analysis of the WOX Gene Family Reveals Evolutionary Conservation and Diversification in Alfalfa

Ecology and Evolution, Volume 16, Issue 8, August 2026.
In this study, we conducted the first integrated pangenome and pan‐transcriptome analysis of the WOX gene family in alfalfa using 24 high‐quality accessions and 43 transcriptome datasets. Our results reveal strong evolutionary conservation dominated by core and soft‐core members, clade‐specific diversification driven mainly by dispersed duplication ...
Hao Wen, Yiwei Bai, Zhao Guo, Wenwu Qian, Yizhi Huang, Yutao Liang, Guodong Yang, Yunwei Zhang   +7 more
wiley   +1 more source

Wilhelm Hofmeister revisited: Meristematic surfaces channel information flows in organogenesis. [PDF]

Quant Plant Biol
Lintilhac PM.
europepmc   +1 more source

Chondroid Soft Tissue Tumors With FOS::PABPN1 Fusion: A New Entity? About Two Cases

Genes, Chromosomes and Cancer, Volume 65, Issue 8, August 2026.
ABSTRACT Soft tissue tumors with chondroid matrix represent a heterogeneous group with persistent diagnostic challenges. Advances in molecular diagnostics have identified recurrent gene fusions in several chondroid neoplasms, predominantly involving FN1. Here, we report two cases of chondroid tumors harboring a novel FOS::PABPN1 fusion.
Jinane Kharmoum, Alexendra Meurgey, Daniel pissaloux, Sanae Chaib, Nicolas Macagno, Mariame Chraibi, Franck Tirode, Marie Karanian   +7 more
wiley   +1 more source

Stage-Dependent Embryolethality of Diclofenac Sodium: Quantitative Assessment of Dose-Time Interaction and Critical Windows of Susceptibility in the In Ovo Chicken Embryo Model. [PDF]

Vet Sci
Kizilay H, Rama ST.
europepmc   +1 more source