Results 51 to 60 of about 47,625 (161)

Optimized Individualized Nursing Improves Recovery and Reduces Complications in ICU Patients with Severe Pneumonia

Organogenesis
Objective This study evaluates the effectiveness of optimized individualized nursing interventions on clinical outcomes in intensive care unit (ICU) patients with severe pneumoniaMethods In this randomized controlled trial, 76 patients with severe ...
Linjuan Wu, Jingchuan Lin
doaj   +1 more source

SS-31 Targets NOS2 to Enhance Osteogenic Differentiation in Aged BMSCs by Restoring Mitochondrial Function

Organogenesis
This study delves into the rejuvenating effects of SS-31 on aged human Bone Marrow-Derived Mesenchymal Stem Cells (BM-MSCs), focusing on its potential to restore their diminished osteogenic differentiation capacity, a critical issue in geriatric medicine
Sen Duan, Qindong Zhang, Jinqiang Zhu, Jiaming Wang   +3 more
doaj   +1 more source

Calcium Imaging in Vivo: How to Correctly Select and Apply Fiber Optic Photometric Indicators

Organogenesis
Fiber-photometric is a novel optogenetic method for recording neural activity in vivo, which allows the use of calcium indicators to observe and study the relationship between neural activity and behavior in free-ranging animals.
Lanxia Wu, Wenxuan Sun, Linjie Huang, Lin Sun, Jinhua Dou, Guohua Lu   +5 more
doaj   +1 more source

A Review of the Risk Factors and Approaches to Prevention of Post-Reperfusion Syndrome During Liver Transplantation

Organogenesis
Post-reperfusion syndrome (PRS) is a severe and highly lethal syndrome that occurs after declamping the portal vein forceps during liver transplantation.
Qian Gao, Jin-Zhen Cai, He Dong
doaj   +1 more source

Lipid Nanovesicle Platforms for Hepatocellular Carcinoma Precision Medicine Therapeutics: Progress and Perspectives

Organogenesis
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality globally. HCC is highly heterogenous with diverse etiologies leading to different driver mutations potentiating unique tumor immune microenvironments.
Brandon M. Lehrich, Evan R. Delgado
doaj   +1 more source

Correlation of MicroRNA-31 with Endometrial Receptivity in Patients with Repeated Implantation Failure of In Vitro Fertilization and Embryo Transfer

Organogenesis
Objective This trial probed the correlation between miR-31 expression and endometrial receptivity (ER) in patients with repeated implantation failure (RIF) of in vitro fertilization and embryo transfer (IVF-ET).Methods A retrospective study of 80 ...
Yan Tan, Bijun Du, Xixi Chen, Minhong Chen   +3 more
doaj   +1 more source

Pnky Modulates Neural Stem Cell Proliferation and Differentiation Through Activation of Wnt/β-Catenin Signaling Pathway

Organogenesis
Neural stem cell (NSC) possess the essential properties of pluripotency and self-renewal, making them promising candidates for the treatment of neurological disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and spinal cord injuries ...
Haidong Wu, Jing Huang, Xiaojing Li, Yali Song, Xuxiang Chen, Yajie Guo   +5 more
doaj   +1 more source

Tetramethylpyrazine Confers Protection Against Oxidative Stress and NLRP3-Dependent Pyroptosis in Rats with Endometriosis

Organogenesis
Tetramethylpyrazine (TMP) has been confirmed to suppress inflammation in endometriosis (EMs). Herein, this study investigated whether and how TMP affected NLRP3 inflammasomes and oxidative stress in EMs. After establishment of an EMs rat model, rats were
Ke Xu, Mingzhe Zhang, Xiaofeng Zou, Mingyang Wang   +3 more
doaj   +1 more source

Optimization of TX-100/SDS-based decellularized vascular material using ultrasound and chemical treatment: evaluation of structure and biosafety

Organogenesis
Decellularized blood vessels with low immunogenicity and excellent biocompatibility are promising for tissue engineering and clinical applications.
Hongguang Chen, Xiaomei Bie, Lifang Hao, HaiGang Jia, Xiufen Li, Chunli Zhang, Jianmei Guo   +6 more
doaj   +1 more source

MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats

Organogenesis
Background This study aimed to determine the potential mechanism by which pancreatic stem cell-derived beta cells (PSCs-β) assist in the body's glucose-lowering capacity in type 1 diabetes (T1D) rats.Methods We screened the transcriptomic changes in the ...
Junling Shan, Huifeng Wang, Guangyu Zhu
doaj   +1 more source