Results 41 to 50 of about 91,856 (332)

Auxin-Regulated Lateral Root Organogenesis.

Cold Spring Harbor Perspectives in Biology, 2021
Plant fitness is largely dependent on the root, the underground organ, which, besides its anchoring function, supplies the plant body with water and all nutrients necessary for growth and development.
N. Cavallari, Christina Artner, E. Benková   +2 more
semanticscholar   +1 more source

Cotyledon organogenesis [PDF]

Journal of Experimental Botany, 2008
The cotyledon represents one of the bases of classification within the plant kingdom, providing the name-giving difference between dicotyledonous and monocotyledonous plants. It is also a fundamental organ and there have been many reports of cotyledon mutants in many species. The use of these mutants where they have arisen in Arabidopsis has allowed us
openaire   +2 more sources

Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

Nature, 2020
Endothelial cells adopt tissue-specific characteristics to instruct organ development and regeneration1,2. This adaptability is lost in cultured adult endothelial cells, which do not vascularize tissues in an organotypic manner.
Brisa Palikuqi, Duc-Huy T. Nguyen, Ge Li, Ryan Schreiner, A. Pellegata, Ying Liu, D. Redmond, Fuqiang Geng, Yang Lin, J. Gómez-Salinero, Masataka Yokoyama, P. Zumbo, Tuo Zhang, Balvir Kunar, Mavee S. Witherspoon, Teng Han, A. Tedeschi, F. Scottoni, S. Lipkin, L. Dow, O. Elemento, J. Xiang, K. Shido, J. Spence, Qiao Zhou, R. Schwartz, P. de Coppi, S. Rabbany, S. Rafii   +28 more
semanticscholar   +1 more source

Cell Aggregation Culture Induces Functional Differentiation of Induced Hepatocyte-like Cells through Activation of Hippo Signaling

Cell Reports, 2018
Summary: Recent progress in direct lineage reprogramming has enabled the generation of induced hepatocyte-like (iHep) cells and revealed their potential as an alternative to hepatocytes for medical applications.
Junpei Yamamoto, Miyako Udono, Shizuka Miura, Sayaka Sekiya, Atsushi Suzuki   +4 more
doaj   +1 more source

In Vitro Characterization of Porcine Hepatocyte Function

Cell Transplantation, 2000
The clinical consequences of acute liver failure are associated with high mortality. Intensive medical intervention is required to treat the symptoms of liver failure, including coagulopathy, metabolic instability, and encephalopathy. Providing temporary
Paul G. Gregory, Christopher K. Connolly, Mehmet Toner, Susan J. Sullivan   +3 more
doaj   +1 more source

Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells

Nature Communications, 2020
The conditions to induce human hepatic progenitor cells from other cell types are unclear. Here, the authors reprogram human endothelial cells to hepatic progenitor cells by expressing FOXA3, HNF1A and HNF6, capable of giving rise to hepatocytes and ...
Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno, Daisuke Saitou, Mikita Suyama, Yoshihiko Maehara, Wataru Kumamaru, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki   +16 more
doaj   +1 more source

BMP Signaling Regulates Bone Morphogenesis in Zebrafish through Promoting Osteoblast Function as Assessed by Their Nitric Oxide Production

Molecules, 2015
Bone morphogenetic proteins (BMPs) control many developmental and physiological processes, including skeleton formation and homeostasis. Previous studies in zebrafish revealed the crucial importance of proper BMP signaling before 48 h post-fertilization (
Thomas Windhausen, Steeve Squifflet, Jörg Renn, Marc Muller   +3 more
doaj   +1 more source

Organ-On-A-Chip: An Emerging Research Platform

Organogenesis, 2023
In drug development, conventional preclinical and clinical testing stages rely on cell cultures and animal experiments, but these methods may fall short of fully representing human biology.
Nithin R, Ayushi Aggarwal, Anne Boyina Sravani, Pooja Mallya, Shaila Lewis   +4 more
doaj   +1 more source

CircHLA-C: A significantly upregulated circRNA co-existing in oral leukoplakia and oral lichen planus

Organogenesis, 2023
Background Oral leukoplakia (OLK) and oral lichen planus (OLP) are common precancerous lesions of the oral mucosa. The role of circular RNAs (circRNAs) in OLK and OLP is unclear.
Jingwen Yang, Yuhan Song, Siming Xu, Shuyun Ge, Zhou Haiwen   +4 more
doaj   +1 more source

Sonic Hedgehog Signaling in Organogenesis, Tumors, and Tumor Microenvironments

International Journal of Molecular Sciences, 2020
During mammalian embryonic development, primary cilia transduce and regulate several signaling pathways. Among the various pathways, Sonic hedgehog (SHH) is one of the most significant. SHH signaling remains quiescent in adult mammalian tissues. However,
K. Jeng, Chiung-Fang Chang, Shuru Lin
semanticscholar   +1 more source