Results 21 to 30 of about 66,436 (284)

Direct Conversion of Human Endothelial Cells Into Liver Cancer‐Forming Cells Using Nonintegrative Episomal Vectors

open access: yesHepatology Communications, 2022
Liver cancer is an aggressive cancer associated with a poor prognosis. Development of therapeutic strategies for liver cancer requires fundamental research using suitable experimental models. Recent progress in direct reprogramming technology has enabled
Takeshi Goya   +6 more
doaj   +1 more source

Regulation of Interferon-β-Modified Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in Proliferation and Apoptosis of Prostate Cancer Cells

open access: yesOrganogenesis, 2023
Prostate cancer (PCa) poses a serious burden to men. Interferon-β (IFN-β) is implicated in cancer cell growth. This study hence explored the regulation of IFN-β-modified human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) in PCa ...
Haichao Yuan   +3 more
doaj   +1 more source

The Role of Gasdermin-D-Mediated Pyroptosis in Organ Injury and Its Therapeutic Implications

open access: yesOrganogenesis, 2023
Gasdermin-D (GSDMD) belongs to the Gasdermin family (GSDM), which are pore-forming effector proteins that facilitate inflammatory cell death, also known as pyroptosis.
Joud Mulla   +2 more
doaj   +1 more source

Lung Organogenesis [PDF]

open access: yes, 2010
Developmental lung biology is a field that has the potential for significant human impact: lung disease at the extremes of age continues to cause major morbidity and mortality worldwide. Understanding how the lung develops holds the promise that investigators can use this knowledge to aid lung repair and regeneration. In the decade since the "molecular
David, Warburton   +13 more
openaire   +2 more sources

Human Hepatocellular response in Cholestatic Liver Diseases

open access: yesOrganogenesis, 2023
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), the most common types of cholestatic liver disease (CLD), result in enterohepatic obstruction, bile acid accumulation, and hepatotoxicity.
Kimberly Ortiz   +9 more
doaj   +1 more source

Adipose-Derived Mesenchymal Stem Cells Attenuate Immune Reactions Against Pig Decellularized Bronchi Engrafted into Rat Tracheal Defects

open access: yesOrganogenesis, 2023
Decellularized scaffolds are promising biomaterials for tissue and organ reconstruction; however, strategies to effectively suppress the host immune responses toward these implants, particularly those without chemical crosslinking, remain warranted ...
Makoto Hisanaga   +14 more
doaj   +1 more source

Thidiazuron-induced shoot organogenesis from mature leaf explants of scented Pelargonium capitatum cultivars [PDF]

open access: yes, 2011
Shoot organogenesis from mature leaf tissues of two scented Pelargonium capitatum cultivars, ‘Attar of Roses’ and ‘Atomic Snowflake’, grown in the greenhouse, were optimized in the presence of thidiazuron (TDZ).
J. Silvestre   +11 more
core   +1 more source

Cells with Many Talents: Lymphatic Endothelial Cells in the Brain Meninges

open access: yesCells, 2021
The lymphatic system serves key functions in maintaining fluid homeostasis, the uptake of dietary fats in the small intestine, and the trafficking of immune cells. Almost all vascularized peripheral tissues and organs contain lymphatic vessels. The brain
Irina Suárez, Stefan Schulte-Merker
doaj   +1 more source

Organogenesis [PDF]

open access: yes, 2020
Abstract This chapter reviews the development of the major organ systems in crustaceans, including musculature, nervous system, circulatory system, digestive system, osmoregulatory system, excretory system, reproductive system, and sensory organs.
Günther Loose   +4 more
openaire   +2 more sources

Thesis Movies - 'Mechanisms of kidney vascularisation and the roles of macrophages in renal organogenesis'

open access: yes, 2018
Movies for the doctoral thesis 'Mechanisms of kidney vascularisation and the roles of macrophages in renal organogenesis'
Munro, David
core   +2 more sources

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