Results 21 to 30 of about 91,856 (332)
Hepatology Communications, 2022 Liver cancer is an aggressive cancer associated with a poor prognosis. Development of therapeutic strategies for liver cancer requires fundamental research using suitable experimental models. Recent progress in direct reprogramming technology has enabled
Takeshi Goya +6 more
doaj +1 more source
Arthritis Research & Therapy, 2022 Background Osteoarthritis is a degenerative disease of the knee that affects 250 million people worldwide. Due to the rising incidence of knee replacement and revision surgery, there is a need for a nonsurgical treatment to reduce pain and improve ...
Kelly A. Kimmerling +3 more
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Organogenesis, 2023 Prostate cancer (PCa) poses a serious burden to men. Interferon-β (IFN-β) is implicated in cancer cell growth. This study hence explored the regulation of IFN-β-modified human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) in PCa ...
Haichao Yuan +3 more
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The Role of Gasdermin-D-Mediated Pyroptosis in Organ Injury and Its Therapeutic Implications
Organogenesis, 2023 Gasdermin-D (GSDMD) belongs to the Gasdermin family (GSDM), which are pore-forming effector proteins that facilitate inflammatory cell death, also known as pyroptosis.
Joud Mulla +2 more
doaj +1 more source
SOX9 in organogenesis: shared and unique transcriptional functions
Cellular and Molecular Life Sciences, 2022 The transcription factor SOX9 is essential for the development of multiple organs including bone, testis, heart, lung, pancreas, intestine and nervous system.
Zhenhua Ming +3 more
semanticscholar +1 more source
Human Hepatocellular response in Cholestatic Liver Diseases
Organogenesis, 2023 Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), the most common types of cholestatic liver disease (CLD), result in enterohepatic obstruction, bile acid accumulation, and hepatotoxicity.
Kimberly Ortiz +9 more
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, 2010 Developmental lung biology is a field that has the potential for significant human impact: lung disease at the extremes of age continues to cause major morbidity and mortality worldwide. Understanding how the lung develops holds the promise that investigators can use this knowledge to aid lung repair and regeneration. In the decade since the "molecular
David, Warburton +13 more
openaire +2 more sources
Organogenesis, 2023 Decellularized scaffolds are promising biomaterials for tissue and organ reconstruction; however, strategies to effectively suppress the host immune responses toward these implants, particularly those without chemical crosslinking, remain warranted ...
Makoto Hisanaga +14 more
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The single cell transcriptional landscape of mammalian organogenesis
Nature, 2019 Mammalian organogenesis is a remarkable process. Within a short timeframe, the cells of the three germ layers transform into an embryo that includes most of the major internal and external organs. Here we investigate the transcriptional dynamics of mouse
Junyue Cao +11 more
semanticscholar +1 more source
Thidiazuron-induced shoot organogenesis from mature leaf explants of scented Pelargonium capitatum cultivars [PDF]
, 2011 Shoot organogenesis from mature leaf tissues of two scented Pelargonium capitatum cultivars, ‘Attar of Roses’ and ‘Atomic Snowflake’, grown in the greenhouse, were optimized in the presence of thidiazuron (TDZ).
J. Silvestre +11 more
core +1 more source