Results 21 to 30 of about 106,456 (270)

Full-thickness dermal wound regeneration using hypoxia preconditioned blood-derived growth factors: A case series

Organogenesis, 2023
Hard-to-heal wounds can be detrimental to patients’ quality of life. Currently, there is scarcity of therapeutic alternatives to mainstay surgical treatment, which uses the principles of tissue debridement, temporary wound coverage, and subsequent tissue
Hadjipanayi Ektoras, Moog Philipp, Jiang Jun, Dornseifer Ulf, Machens Hans-Günther, Schilling Arndt F   +5 more
doaj   +1 more source

Cotyledon organogenesis [PDF]

Journal of Experimental Botany, 2008
The cotyledon represents one of the bases of classification within the plant kingdom, providing the name-giving difference between dicotyledonous and monocotyledonous plants. It is also a fundamental organ and there have been many reports of cotyledon mutants in many species. The use of these mutants where they have arisen in Arabidopsis has allowed us
openaire   +2 more sources

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors. [PDF]

, 2015
The genomic regulatory programmes that underlie human organogenesis are poorly understood. Pancreas development, in particular, has pivotal implications for pancreatic regeneration, cancer and diabetes.
A Kapoor, A Krapp, A Rada-Iglesias, A Sawada, A-C Binot, AF Hezel, AJ Saldanha, B Zhao, B Zhao, C Cortijo, C Haumaitre, C Trapnell, CHH Cho, CY McLean, DA Stoffers, DW Huang, E Kroon, E Rodríguez-Seguel, EF Chiang, F Argenton, F Esni, F Supek, FC Lynn, FC Pan, H Fang, H Fang, H Lango Allen, I Morán, I Rooman, J Bessa, J van Arensbergen, JM Oliver-Krasinski, K Kawakami, K Piper, K Piper, K Skouloudaki, KJ Gaulton, KM Petzold, KS Zaret, L Elghazi, L Pasquali, M Borowiak, M Carrasco, M Gannon, MA Maestro, MC Whitlock, MF Offield, MJL de Hoon, MN Weedon, MP Creyghton, N Bardeesy, N Gao, NM George, P Jacquemin, PA Seymour, R O’Rahilly, R Xie, RE Jennings, RF Luco, S Gupta, S Heinz, S Xuan, T Derrien, T Jowett, W Zhang, WA Whyte, Y Fujitani, Y Liu-Chittenden   +67 more
core   +2 more sources

Cell Aggregation Culture Induces Functional Differentiation of Induced Hepatocyte-like Cells through Activation of Hippo Signaling

Cell Reports, 2018
Summary: Recent progress in direct lineage reprogramming has enabled the generation of induced hepatocyte-like (iHep) cells and revealed their potential as an alternative to hepatocytes for medical applications.
Junpei Yamamoto, Miyako Udono, Shizuka Miura, Sayaka Sekiya, Atsushi Suzuki   +4 more
doaj   +1 more source

In Vitro Characterization of Porcine Hepatocyte Function

Cell Transplantation, 2000
The clinical consequences of acute liver failure are associated with high mortality. Intensive medical intervention is required to treat the symptoms of liver failure, including coagulopathy, metabolic instability, and encephalopathy. Providing temporary
Paul G. Gregory, Christopher K. Connolly, Mehmet Toner, Susan J. Sullivan   +3 more
doaj   +1 more source

Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells

Nature Communications, 2020
The conditions to induce human hepatic progenitor cells from other cell types are unclear. Here, the authors reprogram human endothelial cells to hepatic progenitor cells by expressing FOXA3, HNF1A and HNF6, capable of giving rise to hepatocytes and ...
Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno, Daisuke Saitou, Mikita Suyama, Yoshihiko Maehara, Wataru Kumamaru, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki   +16 more
doaj   +1 more source

Organogenesis

Chinese Medical Journal, 2019
This chapter focuses on organogenesis. It looks into the process of developing organs such as vertebrate eyes, vertebrate heart, teeth, vertebrate lungs, vertebrate limb, and insect wings. The chapter also highlights the complexity of organogenesis as it involves large numbers of genes and different types of tissues while ensuring integrated ...
Lewis Wolpert, Cheryll Tickle, Alfonso Martinez Arias, Peter Lawrence, James Locke   +4 more
openaire   +4 more sources

BMP Signaling Regulates Bone Morphogenesis in Zebrafish through Promoting Osteoblast Function as Assessed by Their Nitric Oxide Production

Molecules, 2015
Bone morphogenetic proteins (BMPs) control many developmental and physiological processes, including skeleton formation and homeostasis. Previous studies in zebrafish revealed the crucial importance of proper BMP signaling before 48 h post-fertilization (
Thomas Windhausen, Steeve Squifflet, Jörg Renn, Marc Muller   +3 more
doaj   +1 more source

Kidney regeneration: common themes from the embryo to the adult [PDF]

, 2013
The vertebrate kidney has an inherent ability to regenerate following acute damage. Successful regeneration of the injured kidney requires the rapid replacement of damaged tubular epithelial cells and reconstitution of normal tubular function ...
Cirio, Maria Cecilia, Davidson, Alan J., de Caestecker, Mark P., de Groh, Eric D., Hukriede, Neil A.   +4 more
core   +1 more source

Loss of pancreas upon activated Wnt signaling is concomitant with emergence of gastrointestinal identity [PDF]

, 2016
Organ formation is achieved through the complex interplay between signaling pathways and transcriptional cascades. The canonical Wnt signaling pathway plays multiple roles during embryonic development including patterning, proliferation and ...
Cano, David A., Flores Martínez, Álvaro, Hebrok, Matthias, Herrero Martín, Griselda, Muñoz Bravo, José Luis, Puri, Sapna, Rojas González, Anabel, Taketo, Makoto Mark   +7 more
core   +8 more sources