Results 11 to 20 of about 47,625 (161)
Developmental lung biology is a field that has the potential for significant human impact: lung disease at the extremes of age continues to cause major morbidity and mortality worldwide. Understanding how the lung develops holds the promise that investigators can use this knowledge to aid lung repair and regeneration. In the decade since the "molecular
David, Warburton +13 more
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Prostate cancer (PCa) poses a serious burden to men. Interferon-β (IFN-β) is implicated in cancer cell growth. This study hence explored the regulation of IFN-β-modified human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) in PCa ...
Haichao Yuan +3 more
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This chapter focuses on organogenesis. It looks into the process of developing organs such as vertebrate eyes, vertebrate heart, teeth, vertebrate lungs, vertebrate limb, and insect wings. The chapter also highlights the complexity of organogenesis as it involves large numbers of genes and different types of tissues while ensuring integrated ...
Arsalan Ahmad +4 more
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The Effect of Coculture with Nonparenchymal Cells on Porcine Hepatocyte Function
Porcine hepatocytes are currently being investigated as a therapy for patients suffering from acute liver failure. Incorporating hepatocytes in an extracorporeal device that would stabilize a patient until transplantation or recovery could dramatically ...
Paul G. Gregory +3 more
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Inexhaustible hair-cell regeneration in young and aged zebrafish
Animals have evolved two general strategies to counter injury and maintain physiological function. The most prevalent is protection by isolating vital organs into body cavities.
Filipe Pinto-Teixeira +6 more
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The Role of Gasdermin-D-Mediated Pyroptosis in Organ Injury and Its Therapeutic Implications
Gasdermin-D (GSDMD) belongs to the Gasdermin family (GSDM), which are pore-forming effector proteins that facilitate inflammatory cell death, also known as pyroptosis.
Joud Mulla +2 more
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Human Hepatocellular response in Cholestatic Liver Diseases
Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), the most common types of cholestatic liver disease (CLD), result in enterohepatic obstruction, bile acid accumulation, and hepatotoxicity.
Kimberly Ortiz +9 more
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Summary: Recent progress in direct lineage reprogramming has enabled the generation of induced hepatocyte-like (iHep) cells and revealed their potential as an alternative to hepatocytes for medical applications.
Junpei Yamamoto +4 more
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Decellularized scaffolds are promising biomaterials for tissue and organ reconstruction; however, strategies to effectively suppress the host immune responses toward these implants, particularly those without chemical crosslinking, remain warranted ...
Makoto Hisanaga +14 more
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The cotyledon represents one of the bases of classification within the plant kingdom, providing the name-giving difference between dicotyledonous and monocotyledonous plants. It is also a fundamental organ and there have been many reports of cotyledon mutants in many species. The use of these mutants where they have arisen in Arabidopsis has allowed us
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