Results 11 to 20 of about 91,856 (332)
Development, 2022 ABSTRACT Prostate organogenesis begins during embryonic development and continues through puberty when the prostate becomes an important exocrine gland of the male reproductive system. The specification and growth of the prostate is regulated by androgens and is largely a result of cell-cell communication between the epithelium and ...
Andrew Pletcher, Maho Shibata
openaire +3 more sources
Simulation and Statistical Techniques to Explore Lymphoid Tissue Organogenesis [PDF]
, 2012 Secondary lymphoid organs have a key role in the initiation of adaptive immune responses to infection. Organogenesis occurs in foetal development, and the use of genetic tools, imaging technologies, and ex vivo culture systems has provided significant ...
Alden, Kieran
core +6 more sources
Current Opinion in Cell Biology, 2021 Organoids are three-dimensional structures that self-organize from human pluripotent stem cells or primary tissue, potentially serving as a traceable and manipulatable platform to facilitate our understanding of organogenesis. Despite the ongoing advancement in generating organoids of diverse systems, biological applications of in vitro generated ...
Kentaro Iwasawa, Takanori Takebe
openaire +2 more sources
Cold Spring Harbor Perspectives in Medicine, 2017 The prostate is a male exocrine gland that secretes components of the seminal fluid. In men, prostate tumors are one of the most prevalent cancers. Studies on the development of the prostate have given a better understanding of the processes and genes that are important in the formation of this organ and have provided insights into the mechanisms of ...
Jeffrey C, Francis, Amanda, Swain
openaire +2 more sources
Human brain organogenesis: Toward a cellular understanding of development and disease
Cell, 2021 SUMMARY The construction of the human nervous system is a distinctly complex although highly regulated process. Human tissue inaccessibility has impeded a molecular understanding of the developmental specializations from which our unique cognitive ...
Kevin W. Kelley, S. Pașca
semanticscholar +1 more source
Long-term in toto Imaging of Cellular Behavior during Nerve Injury and Regeneration
Bio-Protocol, 2023 Accidental wounding of the peripheral nervous system leads to acute neural dysfunction. Normally, chronic deficits are overcome because peripheral nerves naturally regenerate.
Weili Tian +2 more
doaj +1 more source
Embryo model completes gastrulation to neurulation and organogenesis
Nature, 2022 Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro1–5, but their developmental potential is substantially extended by interactions with extraembryonic stem cells, including trophoblast stem (TS) cells, extraembryonic ...
G. Amadei +14 more
semanticscholar +1 more source
Nature Communications, 2021 Soft tissue trauma can result in aberrant osteochondral differentiation of local mesenchymal progenitor cells. Here the authors show that, in mice, soft tissue trauma results in NGF expression by perivascular cells, which leads to axonal invasion and ...
Seungyong Lee +23 more
doaj +1 more source
Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis
Immunity, 2017 Mario Novković +2 more
exaly +2 more sources
Synthetic dynamic hydrogels promote degradation-independent in vitro organogenesis
Nature Materials, 2021 Epithelial organoids are most efficiently grown from mouse-tumour-derived, reconstituted extracellular matrix hydrogels, whose poorly defined composition, batch-to-batch variability and immunogenicity limit clinical applications.
Antonius Chrisnandy +4 more
semanticscholar +1 more source