Results 71 to 80 of about 137,132 (345)

A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis [PDF]

, 2016
During late gestation, villi extend into the intestinal lumen to dramatically increase the surface area of the intestinal epithelium, preparing the gut for the neonatal diet.
Bonder, Edward M., Faller, William J., Gao, Nan, Gumucio, Deborah L., Joshi, Shilpy, Kumar, Namit, Perekatt, Ansu O., Sansom, Owen J., Srivillibhuthur, Manasa, Verzi, Michael P., Walton, Katherine D., White, Eileen, Xing, Jinchuan, Zhou, Anbo   +13 more
core   +1 more source

Cyborg Organoids: Implantation of Nanoelectronics via Organogenesis for Tissue-Wide Electrophysiology

bioRxiv, 2019
Tissue-wide electrophysiology with single-cell and millisecond spatiotemporal resolution is critical for heart and brain studies, yet issues arise from invasive, localized implantation of electronics that destructs the well-connected cellular networks ...
Qiang Li, Kewang Nan, P. Le Floch, Zuwan Lin, Hao Sheng, Thomas S Blum, Jia Liu   +6 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Thrombospondin 1 and 2 regulate mesenchymal progenitor cell fate and matrix organization

Bone Research
Thrombospondin 1 and 2 (TSP1 and TSP2) are critical regulators of extracellular matrix (ECM) interactions, influencing cell differentiation and tissue repair.
Madysen K. Hunter, Sneha Korlakunta, Neda Vishlaghi, Monisha Mittal, Kyle Cragg, Conan Juan, Chase A. Pagani, Yuxiao Sun, Lindsey Lammlin, Karen Kessell, Dylan Feist, Ji Hae Choi, Meng-Lun Hsieh, Jahnu Saikia, Craig L. Duvall, Heeseog Kang, Andrea I. Alford, Kurt D. Hankenson, Robert J. Tower, Tristan Maerz, Benjamin Levi   +20 more
doaj   +1 more source

Regeneration of begonia plantlets by direct organogenesis [PDF]

, 2009
The economic importance of ornamentals worldwide suggests a bright future for ornamental breeding. Rapid progress in plant molecular biology has great potentials to contribute to the breeding of novel ornamental plants utilizing recombinant DNA ...
Curuk, P., Eldoğan, S., Gencel, G., Kocaman, E., Mendi, Yalçın Y., Unek, C., Çetiner, Selim   +6 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The tailless Ortholog nhr-67 Regulates Patterning of Gene Expression and Morphogenesis in the C. elegans Vulva [PDF]

, 2007
Regulation of spatio-temporal gene expression in diverse cell and tissue types is a critical aspect of development. Progression through Caenorhabditis elegans vulval development leads to the generation of seven distinct vulval cell types (vulA, vulB1 ...
Fernandes, Jolene S., Sternberg, Paul W.
core   +9 more sources

Cytokinin response factors regulate PIN-FORMED auxin transporters [PDF]

, 2015
Auxin and cytokinin are key endogenous regulators of plant development. Although cytokinin-mediated modulation of auxin distribution is a developmentally crucial hormonal interaction, its molecular basis is largely unknown.
Beeckman, Tom, Benkova, Eva, Braun Šimášková, Mária, Cuesta, Candela, De Clercq, Inge, Friml, Jiri, Hoyerová, Klára, Khan, Mamoona, Marhavy, Peter, Murphy, Angus, Nowack, Moritz, O'Brien, Jose Antonio, Otvos, Krisztina, Van Breusegem, Frank, Van Haperen, Johanna Maria Adriana, Van Noorden, Giel, Vanneste, Steffen, Vieten, Anne, Wabnik, Krzysztof, Weijers, Dolf   +19 more
core   +5 more sources

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

dab2 is required for the scavenging function of lymphatic endothelial cells in the zebrafish meninges

Scientific Reports
To date it is only partially understood how the brain is cleared of waste products resulting from its high metabolic activity, although this process has important implications for the development and progression of neurodegenerative diseases.
Katharina Uphoff, Irina Suárez, Andreas van Impel, Stefan Schulte-Merker   +3 more
doaj   +1 more source