Results 71 to 80 of about 136,612 (370)

dab2 is required for the scavenging function of lymphatic endothelial cells in the zebrafish meninges

Scientific Reports
To date it is only partially understood how the brain is cleared of waste products resulting from its high metabolic activity, although this process has important implications for the development and progression of neurodegenerative diseases.
Katharina Uphoff, Irina Suárez, Andreas van Impel, Stefan Schulte-Merker   +3 more
doaj   +1 more source

The role of pioneer transcription factors in the induction of direct cellular reprogramming

Regenerative Therapy, 2023
Regenerative medicine is a highly advanced medical field that aims to restore tissues and organs lost due to diseases and injury using a person's own cells or those of others.
Kenichi Horisawa, Atsushi Suzuki
doaj   +1 more source

De novo shoot organogenesis during plant regeneration.

Journal of Experimental Botany, 2019
Plants exhibit remarkable regeneration capacity, ensuring developmental plasticity. In vitro tissue culture techniques are based on the plant regeneration ability and facilitate production of new organs and even whole plant from explants.
Jinwoo Shin, S. Bae, P. Seo
semanticscholar   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

The Interactivity between TGFβ and BMP Signaling in Organogenesis, Fibrosis, and Cancer

Cells, 2019
The Transforming Growth Factor beta (TGFβ) and Bone Morphogenic Protein (BMP) pathways intersect at multiple signaling hubs and cooperatively or counteractively participate to bring about cellular processes which are critical not only for tissue ...
F. Dituri, C. Cossu, Serena Mancarella, G. Giannelli   +3 more
semanticscholar   +1 more source

A statistical model for analyzing jointly growth phases, the influence of environmental factors and inter-individual heterogeneity : Applications to forest trees [PDF]

, 2007
International ...
Caraglio, Yves, Chaubert, Florence, Guédon, Yann, Lavergne, Christian, Trottier, Catherine   +4 more
core   +1 more source

The PIN-FORMED (PIN) protein family of auxin transporters [PDF]

, 2009
The PIN-FORMED (PIN) proteins are secondary transporters acting in the efflux of the plant signal molecule auxin from cells. They are asymmetrically localized within cells and their polarity determines the directionality of intercellular auxin flow.
Friml, Jiri, Krecek, Pavel, Libus, Jiri, Naramoto, Satoshi, Skupa, Petr, Tejos Ulloa, Ricardo, Zazimalova, Eva   +6 more
core   +3 more sources

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Machine Learning Technology Reveals the Concealed Interactions of Phytohormones on Medicinal Plant In Vitro Organogenesis

Biomolecules, 2020
Organogenesis constitutes the biological feature driving plant in vitro regeneration, in which the role of plant hormones is crucial. The use of machine learning (ML) technology stands out as a novel approach to characterize the combined role of two ...
P. García-Pérez, Eva Lozano-Milo, M. Landín, P. Gallego   +3 more
semanticscholar   +1 more source

Cytokinin response factors regulate PIN-FORMED auxin transporters [PDF]

, 2015
Auxin and cytokinin are key endogenous regulators of plant development. Although cytokinin-mediated modulation of auxin distribution is a developmentally crucial hormonal interaction, its molecular basis is largely unknown.
Beeckman, Tom, Benkova, Eva, Braun Šimášková, Mária, Cuesta, Candela, De Clercq, Inge, Friml, Jiri, Hoyerová, Klára, Khan, Mamoona, Marhavy, Peter, Murphy, Angus, Nowack, Moritz, O'Brien, Jose Antonio, Otvos, Krisztina, Van Breusegem, Frank, Van Haperen, Johanna Maria Adriana, Van Noorden, Giel, Vanneste, Steffen, Vieten, Anne, Wabnik, Krzysztof, Weijers, Dolf   +19 more
core   +5 more sources