Results 71 to 80 of about 136,156 (356)

Oligohistidine‐Functionalized Single‐Walled Carbon Nanotube‐Guided RNA Delivery to Improve Shoot Regeneration Efficiency in Plant Calli

open access: yesAdvanced Functional Materials, EarlyView.
The pH‐sensitive His6‐SWNTs, which is functionalized with oligohistidine, can deliver STTM396 molecules into callus cells. The STTM396–SWNT complex treatments enhance shoot regeneration efficiency by regulating the miR396‐GRF module in Arabidopsis and tomato calli.
Yeong Yeop Jeong   +7 more
wiley   +1 more source

Cell polarity and patterning by PIN trafficking through early endosomal compartments in Arabidopsis thaliana [PDF]

open access: yes, 2013
PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants.
De Rycke, Riet   +8 more
core   +9 more sources

The Interactivity between TGFβ and BMP Signaling in Organogenesis, Fibrosis, and Cancer

open access: yesCells, 2019
The Transforming Growth Factor beta (TGFβ) and Bone Morphogenic Protein (BMP) pathways intersect at multiple signaling hubs and cooperatively or counteractively participate to bring about cellular processes which are critical not only for tissue ...
F. Dituri   +3 more
semanticscholar   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney   +3 more
wiley   +1 more source

Machine Learning Technology Reveals the Concealed Interactions of Phytohormones on Medicinal Plant In Vitro Organogenesis

open access: yesBiomolecules, 2020
Organogenesis constitutes the biological feature driving plant in vitro regeneration, in which the role of plant hormones is crucial. The use of machine learning (ML) technology stands out as a novel approach to characterize the combined role of two ...
P. García-Pérez   +3 more
semanticscholar   +1 more source

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

open access: yesAdvanced Science, EarlyView.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang   +6 more
wiley   +1 more source

Spatial and temporal patterns of distribution of the gap junction protein connexin43 during mouse gastrulation and organogenesis [PDF]

open access: yes, 1992
Connexin43 (Cx43) is a member of the family of channel-forming proteins that make up the gap junction and are believed to provide pathways for cell-cell exchange of developmental signals.
Biswal, Sandip   +2 more
core  

The PIN-FORMED (PIN) protein family of auxin transporters [PDF]

open access: yes, 2009
The PIN-FORMED (PIN) proteins are secondary transporters acting in the efflux of the plant signal molecule auxin from cells. They are asymmetrically localized within cells and their polarity determines the directionality of intercellular auxin flow.
Friml, Jiri   +6 more
core   +3 more sources

Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration

open access: yesAdvanced Science, EarlyView.
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin   +7 more
wiley   +1 more source

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