Results 181 to 190 of about 58,747 (290)

Multiscale imaging of polarity in bovine oviductal organoids. [PDF]

Front Cell Dev Biol
Dunn B, Meyers MA, Burlingham S, Morisaki T, Darehshouri A, Gad A, Thompson-Brandhagen R, Stasevich TJ, Hollinshead FK.   +8 more
europepmc   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Modeling gliomas with organoids: reconstructing the human neural microenvironment for translational neuro-oncology. [PDF]

Front Oncol
Ishan M, Jimenez-Macias JL, Read RD.
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdown. [PDF]

Front Cell Dev Biol
Rojo C, Vila JJ, Guembe L, Arrubla-Gamboa A, Jusué-Irurita V, Carrascosa-Gil J, Rullan M, Rández-Garbayo J, Fernández-Barrena MG, Huch M, Urman J, Ávila MA, Berasain C, Arechederra M.   +13 more
europepmc   +1 more source

Recent Advances in Graphene Oxide-Based on Organoid Culture as Disease Model and Cell Behavior – A Systematic Literature Review

Haura Labibah Salsabil Sulaksono,1,* Annisa Annisa,2,* Rovina Ruslami,3,* Mufeeduzzaman Mufeeduzzaman,4,* Camellia Panatarani,4,5,* Wawan Hermawan,2,4,* Savira Ekawardhani,3,4,* I Made Joni4,5,* 1Department of ...
Sulaksono HLS, Panatarani C, Joni IM, Ruslami R, Mufeeduzzaman M, Hermawan W, Annisa A, Ekawardhani S   +7 more
core  

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

Advanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang, Xin He, Hao Huang, Rong Lu, Xin Lv, Shenglan Li, Sijue Zou, Jiawei Cheng, Yiwei Xiong, Zhenghao Deng, Qiongjing Yuan, Yanyun Xie, Ling Huang, Jiaxi Pu, Shao Liu, Qianbin Li, Jie Meng, Huixiang Yang, Lijian Tao, Zhangzhe Peng   +19 more
wiley   +1 more source

Corrigendum to 'Establishment and characterization of an inflammatory cartilaginous organoids model for organoid transplantation study' [J Orthop Transl 52, May 2025, Pages 376-386]. [PDF]

J Orthop Translat
Zhang Y, Fang Q, Peng Y, Liu H, Tang J, Ma R, Wang W.   +6 more
europepmc   +1 more source

Development of a Human 3D Immune‐Competent Neurovascular Model Enabling Time‐Resolved Monitoring of Neuroinflammatory Dynamics and Neuroimmune Interactions

Advanced Science, EarlyView.
Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk, Jing Bai, Olurotimi A. Bolonduro, Andrew M. Silverman, Robert Madison Green, Jason H. Lasser, Paul W. Fleming, Lishomwa C. Ndhlovu, James F. Saunders, Dmitry Shvartsman   +9 more
wiley   +1 more source

Multiparametric dynamic optical coherence tomography for evaluation of human cardiac organoids subjected to external stress. [PDF]

Biomed Opt Express
Shitiri NC, Le TD, Yoo SJ, Cho M, Kim YS, Ahn Y, Lee C.   +6 more
europepmc   +1 more source