Results 251 to 260 of about 114,312 (393)

Differential Modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of Host Peripheral Lipid Metabolism and Histone Acetylation in Mouse Gut Organoids

, 2014
Sabina Lukovac, Clara Belzer, Linette Pellis, Bart J. F. Keijser, Willem M. de Vos, R.C. Montijn, Guus Roeselers   +6 more
openalex   +1 more source

Neural organoids for disease phenotyping, drug screening and developmental biology studies [PDF]

, 2016
Brigham J. Hartley, Kristen Brennand
openalex   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

Advanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao, Yu‐Bo Ma, Rui‐Hong Xia, Zheng‐Chen Jiang, Ying Zhou, Ya‐Nan Wang, Meng‐Yan Yang, Jing‐Jie Dai, Tao Zhu, Li‐Bin Pan, Li Yuan   +10 more
wiley   +1 more source

Brain‐inspired intelligence‐driven scientific research

Brain-X
Long Bai, Jiacan Su
doaj   +1 more source

Wnt/β-Catenin Pathway Activation Confers Fumonisin B1 Tolerance in Chicken Intestinal Organoid Monolayers by Enhancing Intestinal Stem Cell Function. [PDF]

Animals (Basel)
Zhang S, Cao Y, Shan Y, Zhang X, Xia L, Wang H, Wu S, Bao W.   +7 more
europepmc   +1 more source

Vascularizing the brain organoids

Journal of Molecular Cell Biology, 2022
Xin-Yao Sun, Zhen-Ge Luo
openaire   +2 more sources

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

Advanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen, Ying Zhang, Zimeng Zhao, Yang Yang, Geng Guo, Yi Sun, Tao Zhang, Zhihong Zhang, Liqin Zeng, Wenxin Huang, Qingjun Shen, Ruining Han, Zhaohui He, Depeng Zhao, Huidong Zhang   +14 more
wiley   +1 more source

Organoid models established from primary tumors and patient-derived xenograft tumors reflect platinum sensitivity of ovarian cancer patients. [PDF]

BMC Cancer
Nikeghbal P, Zamanian D, Burke D, Steinkamp MP.   +3 more
europepmc   +1 more source

Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine

, 2014
Sean R. Moore, Jill Pruszka, Jefferson E. Vallance, Eitaro Aihara, Toru Matsuura, Marshall H. Montrose, Noah F. Shroyer, Christian I. Hong   +7 more
openalex   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source