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Rapid establishment of KRAS-driven bladder cancer initiation and immune escape models using genetically engineered mice and organoid approaches. [PDF]
Front ImmunolYang G +7 more
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Single-cell transcriptomic mapping of patient-derived primary liver cancer organoids reveals molecular subtypes and guides precision drug targeting. [PDF]
Cell Oncol (Dordr)Dai S +16 more
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Cryoletters, 2023
Organoids represent indispensable opportunities for biomedicine, including drug discovery, cancer biology, regenerative and personalised medicine or tissue and organ transplantation. However, the lack of optimised preservation strategies limits the wide use of organoids in research or clinical fields.
O, Rogulska, J, Havelkova, Y, Petrenko
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Organoids represent indispensable opportunities for biomedicine, including drug discovery, cancer biology, regenerative and personalised medicine or tissue and organ transplantation. However, the lack of optimised preservation strategies limits the wide use of organoids in research or clinical fields.
O, Rogulska, J, Havelkova, Y, Petrenko
openaire +2 more sources
Nature Reviews Cancer, 2019
Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
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Neal et al. have successfully established patient-derived organoids of tumour epithelia retaining native immune cells, thereby recapitulating tumour microenvironment diversity and enabling immuno-oncology studies.
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Commercialization of Organoids
Trends in Molecular Medicine, 2020Organoids have been successfully exploited for drug screening, disease modeling, pathogenesis, and regenerative medicine. Herein, we discuss the progress achieved in the commercialization of organoids in the last few years. We further elaborate on the concept of organoid biobank and highlight ethical and regulatory issues surrounding organoid research ...
Deepak, Choudhury +2 more
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Nature Biotechnology, 2019
Human brain organoids are endowed with regional topography using engineered signaling centers.
Yuki Miura, Sergiu P. Pașca
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Human brain organoids are endowed with regional topography using engineered signaling centers.
Yuki Miura, Sergiu P. Pașca
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Generation of Organoids and Analysis of Ferroptosis in Organoids
2023Ferroptosis is a unique form of iron-dependent cell death induced by lipid peroxidation and subsequent plasma membrane rupture, which sets it apart from other types of regulated cell death. Ferroptosis has been linked to a diverse range of biological processes, such as aging, immunity, and cancer. Organoids, on the other hand, are three-dimensional (3D)
Wenxin, Li +4 more
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