Results 251 to 260 of about 74,769 (302)

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

Advanced Science, EarlyView.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang, Yisong Huang, Weijian Zhao, Tian Chen, Siyu Bai, Denghui Guo, Mengying Wang, Yaoyao Zhao, Liang Zhao, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

Patient-derived epithelial cell organoids mimic the phenotypic complexity of endometriosis subtypes. [PDF]

Hum Reprod
Gunther K, Liu D, Cortesi M, Powell E, Nesbitt-Hawes E, Abbott JA, Ford CE.   +6 more
europepmc   +1 more source

Deep Volumetric Super‐Resolution Imaging in Thick Biological Specimens With Sparse Scanning SIM

Advanced Science, EarlyView.
Sparse scanning structured illumination microscopy (SS‐SIM) extends the axial depth in super‐resolution fluorescence imaging by combining rapid laser scanning, pixel‐addressed intensity modulation, and sCMOS camera detection. SS‐SIM yields 1.6× lateral and 1.7× axial resolution gains over wide‐field microscopy and enables imaging through 300–600 µm ...
Sha An, Xuhong Guo, Zhongxia Cai, Yunze Lei, Kai Wen, Hongfei Suo, Xiaoyu Kong, Gerd Ulrich Nienhaus, Peng Gao   +8 more
wiley   +1 more source

Modeling ALS in a dish: how organoids are transforming research. [PDF]

Front Med (Lausanne)
Galluzzi G, Ruocco G, Fornetti E, Genovese I.   +3 more
europepmc   +1 more source

Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation

Advanced Science, EarlyView.
Nanoplastics are pervasive environmental contaminants with potentially profound implications for human health. Emerging evidence suggests a possible link between nanoplastic exposure and neurodegeneration, a key driver of ageing and dementia, yet causality remains unresolved.
Yuhuan Li, Yue Wang, Xiufang Liang, Mengze Xu, David T. Leong, Pu Chun Ke   +5 more
wiley   +1 more source

Preclinical Combination Targeting VEGF and PI3K in a Rare, Aggressive Mixed Endometrial Carcinoma: An Applied Case Report. [PDF]

Cancer Res Commun
Radulovich N, Pina PS, Udaskin ML, Li Q, Nixon KCJ, Xie IY, Nand A, Rosen JC, Li M, Hodgson A, Pham NA, Oza AM, Lupien M, Rottapel R, Tsao MS, Lheureux S.   +15 more
europepmc   +1 more source

NICI organoid culture bank with 90 organoids

AMC will deliver 3 samples from 30 patients (patientderived oesophageal and pancreatic cancer organoids from an existing organoid culture bank covering the entire spectrum of tumour heterogeneity) to prof Burgering (UMCU). A report will be written on the establishment of the organoid culture bank.
openaire   +1 more source

Protocol for characterization of spatiotemporal network dynamics in cortical and hippocampal assembloids. [PDF]

STAR Protoc
Guzman AR, McCrimmon CM, Toker D, Novitch BG, Watanabe M, Samarasinghe RA.   +5 more
europepmc   +1 more source