Results 101 to 110 of about 1,044,908 (274)

Bone organoid construction and evolution

Journal of Orthopaedic Translation
Organoids, generated through three-dimensional in vitro culture, are cellular aggregates that accurately mimic the complex microenvironment, cell–cell interactions, and signaling mechanisms of native tissues.
Yang Hong, Ruiyang Li, Shihao Sheng, Fengjin Zhou, Long Bai, Jiacan Su   +5 more
doaj   +1 more source

Real‐Time, Label‐Free Classification of Cell Death Pathways via Holotomography‐Based Deep Learning Framework

Advanced Intelligent Systems, EarlyView.
A 3D holotomography system coupled with a deep learning model distinguishes how cells die—apoptosis, necroptosis or necrosis—without any fluorescent labels. Training on refractive index maps of HeLa cells yields 97% accuracy and flags necroptosis hours before chemical dyes.
Minwook Kim, Wei Sun Park, Geon Kim, Sanggeun Oh, Jaephil Do, Juyeon Park, Jihwan Yu, Won Do Heo, YongKeun Park   +8 more
wiley   +1 more source

Device‐Level Implementation of Reservoir Computing With Memristors

Advanced Intelligent Systems, EarlyView.
Reservoir computing (RC) is an emerging computing scheme that employs a reservoir and a single readout layer, which can be actualized in the nanoscale with memristors. As a comprehensive overview, the principles of RC and the switching mechanisms of memristors are discussed, followed by actual demonstrations of memristor‐based RC and the remaining ...
Sunbeom Park, Hyojung Kim, Ho Won Jang
wiley   +1 more source

Building Immunocompetent Cerebral Organoids From a Developmental Perspective [PDF]

Cerebral organoids derived from human induced pluripotent stem cells (iPSCs) are increasingly becoming essential tools to study the human brain, from understanding pathological mechanisms in neurodevelopmental, neurodegenerative, and infectious diseases ...
Bengoa‐Vergniory, Nora, Cavaliere, Fabio, Cuesta‐Puente, Xabier, Gonzalez‐Dominguez, Marco, Pereira‐Iglesias, Marta, Perez‐Arriazu, Nerea, Ramos‐Gonzalez, Paula, Sierra, Amanda, Villegas‐Zafra, Patricia   +8 more
core   +2 more sources

Integrating Artificial Intelligence With Droplet‐Based Microfluidics: Advances, Challenges, and Emerging Opportunities

Advanced Intelligent Systems, EarlyView.
Droplet‐based microfluidics enables precise, high‐throughput microscale reactions but continues to face challenges in scalability, reproducibility, and data complexity. This review examines how artificial intelligence enhances droplet generation, detection, sorting, and adaptive control and discusses emerging opportunities for clinical and industrial ...
Junyan Lai, Sukrit Gaira, Rongfeng Wang, Qingtian Zhang, Ming Li, Liao Wu, Diangeng Li, Yi Li, Chengchen Zhang, Jinhong Guo, Shi‐Yang Tang   +10 more
wiley   +1 more source

Building an Intelligent Cardiovascular System Platform: Embedding Artificial Intelligence across All Facets of Cardiovascular Medicine

Advanced Intelligent Systems, EarlyView.
This paper presents an integrated AI‐driven cardiovascular platform unifying multimodal data, predictive analytics, and real‐time monitoring. It demonstrates how artificial intelligence—from deep learning to federated learning—enables early diagnosis, precision treatment, and personalized rehabilitation across the full disease lifecycle, promoting a ...
Mowei Kong, Xingwei Zhao, Qiuting Li, Yang Yu, Chunxiang Zhang   +4 more
wiley   +1 more source

Transformasi Biomedik Menuju Personalisasi dan Kesehatan Presisi pada Kanker [PDF]

Biomedical transformation is redefining cancer research and clinical practice by integrating experimental and computational approaches, digital technologies, and patient-specific models to realize precision health. Wet lab experiments generate molecular,
Ghanny, Niken Rahmah, Indarjo, Pararawendy, Rahajeng, Herera   +2 more
core   +2 more sources

An Ethical Analysis of Human Cerebral Organoids

Yixue yu zhexue
Human cerebral organoids are three-dimensional neural tissues with similar structure and biological function to human brain. Human cerebral organoids can be used to study human brain development, disease mechanisms, and drug screening.
Bin HUANG
doaj   +1 more source

Brain organoid methodologies to explore mechanisms of disease in progressive multiple sclerosis. [PDF]

Multiple sclerosis (MS), a debilitating autoimmune disorder targeting the central nervous system (CNS), is marked by relentless demyelination and inflammation.

core   +1 more source

Precision modulation of tumor excitability: Targeting cell phenotypic heterogeneity for next‐generation cancer therapy

BMEMat, EarlyView.
This Perspective introduces tumor electrical excitability as a previously overlooked dimension of cancer biology. It proposes that tumor–neural interactions enable malignant cells to acquire neuron‐like properties and form bidirectional chemical and electrical communications with nerves.
Zonghao Liu, Xingwu Jiang, Gang Liu, Jian Chen, Kun Song, Xu Li, Siew Yee Wong, Ruicheng Shi, Yanyan Liu, Wenbo Bu   +9 more
wiley   +1 more source