Beyond single cells: Ten years of commercial lattice light‐sheet microscopy
Abstract Lattice light‐sheet microscopy (LLSM) enables gentle, rapid, volumetric fluorescence imaging of living biological systems. The technique employs Bessel beam interference to produce a light‐sheet which retains its thickness over a relatively large field‐of‐view compared to other light‐sheets.
Helena L. E. Coker, David S. Corcoran
wiley +1 more source
Patient-derived intestinal organoids in pediatric inflammatory bowel disease: applications in disease modeling and therapeutic response prediction. [PDF]
Cho KY.
europepmc +1 more source
napari‐lattice: A user‐friendly image processing tool for lattice light‐sheet microscopy data
Abstract Lattice light‐sheet microscopy (LLSM) has revolutionised live‐cell imaging with its ability to resolve sub‐cellular detail with high spatiotemporal resolution and minimal phototoxicity. However, LLSM often generates large terabyte‐scale datasets that require complex preprocessing, creating bottlenecks in storage, data handling and analysis ...
Pradeep Rajasekhar +9 more
wiley +1 more source
Advances in organoids for personalized medicine: from technological development to clinical application. [PDF]
Zhou X +8 more
europepmc +1 more source
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva +19 more
wiley +1 more source
Engineering brain organoids for functional validation and translational applications: Construction strategies, vascularization, and standardization. [PDF]
Huang G +11 more
europepmc +1 more source
The Physical and Computational Boundaries of Organoid Intelligence
Recent paradigms in Organoid Intelligence (OI) frequently characterize in vitro neural networks using cognitive metaphors. This manuscript rejects teleological metaphors, strictly framing human brain organoids as physical substrates undergoing local thermodynamic relaxation following external perturbations.
openaire +1 more source
Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
The US Religious Public and Radical Human Enhancements
ABSTRACT A radical enhancement to the human body or brain is defined as giving human capabilities that no past or present human has possessed. These are being developed by scientists and bioengineers and backed by Silicon Valley entrepreneurs. This article reports on the first study of the US religious public's views of radical enhancements using a ...
John H. Evans
wiley +1 more source
Building bridges to immunotherapy: a knowledge-mapping analysis of cervical cancer organoid research. [PDF]
Tian Y +7 more
europepmc +1 more source

