Results 41 to 50 of about 2,401,578 (298)
Microengineered organoids: reconstituting organ-level functions in vitro [PDF]
, 2023 In vitro miniaturized organoids are innovative tools with varying applications in biomedical engineering, such as drug testing, disease modeling, organ development studies, and regenerative medicine. However, conventional organoid development has several
Harshita Sharma +6 more
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Human brain organoids in Alzheimer’s disease [PDF]
, 2021 Alzheimer’s disease (AD) is a progressive neurological disorder that typically involves neuronal damage leading to the deterioration of cognitive and essential body functions in aging brains.
Hansang Cho, You Jung Kang
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Lung organoids: target cells for understanding respiratory diseases [PDF]
, 2021 Human respiratory disease research currently lacks in vitro models that recapitulate most of the physiology and architecture of the lung. Furthermore, the complex composition and structure of the lung, as well as anatomical differences between humans and
Se-Ran Yang, Jooyeon Lee
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Clinical applications and optimization of patient-derived organoids in intestinal diseases [PDF]
, 2022 Since the first successful establishment of organoids from adult intestinal stem cells, organoid technology has rapidly developed. With advances in normal organoid technology, intestinal disorders, such as colorectal tumors and inflammatory bowel disease,
Tae Il Kim
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Disease modeling and drug screening using human airway organoids: a systematic review [PDF]
, 2021 Increasing levels of fine environmental dust particles due to industrialization and emerging respiratory illnesses, such as coronavirus disease 2019, pose serious threats to human life.
Sung Won Kim, Do Hyun Kim
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Organoid intelligence: smarter than the average cell culture
Frontiers in Science, 2023 COPYRIGHT © 2023 Miller. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright
G. Miller
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npj Precision Oncology, 2023 Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases, characterized by a treatment-resistant and invasive nature. In line with these inherent aggressive characteristics, only a subset of patients shows a clinical response to the ...
Maxim Le Compte +15 more
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Cancer Biology & Medicine, 2023 Objective: Organoids are a powerful tool with broad application prospects in biomedicine. Notably, they provide alternatives to animal models for testing potential drugs before clinical trials. However, the number of passages for which organoids maintain
Ruixin Yang +9 more
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Organoid Intelligence: Bridging the Gap between Biological and Artificial Neural Networks ()
International Journal of Intelligence ScienceGobind Naidu +2 more
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Emerging organoid-based platforms to study salivary gland hypofunction [PDF]
, 2022 Xerostomia is a pathologic condition of hyposalivation due to salivary gland (SG) dysfunction. Although xerostomia significantly affects the quality of patients’ life, there is no satisfactory treatment for this disease.
Yoojin Seo, Hyung-Sik Kim
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