Results 211 to 220 of about 120,310 (351)

Glucose levels impact the morphology and cell-type composition of human cerebral organoids [PDF]

Gautami R Kelkar, Balaji M. Rao, Albert J. Keung   +2 more
openalex   +1 more source

Nanomaterial‐Based Muscle Cell/Neural Tissue Biohybrid Robots: From Actuation to Biomedical Applications

Advanced Robotics Research, EarlyView.
Muscle cell‐based biohybrid robot using nanomaterials for function enhancement and neural function for biomedical applications. Biohybrid robotics, an emerging field combining biological tissues with artificial systems, has made significant progress in developing various biohybrid constructs, including muscle‐cell‐driven biorobots and microbots.
Minkyu Shin, Sangeun Lee, Su Ryon Shin, Jin‐Ha Choi, Jeong‐Woo Choi   +4 more
wiley   +1 more source

Establishment of Mouse Meibomian Gland Organoids for In Vitro Modeling of Meibomian Gland Dysfunction. [PDF]

Invest Ophthalmol Vis Sci
Qu J, Yang L, Wang X, Zhao L, Li Z, Zhang X, Lin Y, Guo Q, Zhao H, Zhong Y, Xie L, Zhou Q.   +11 more
europepmc   +1 more source

P026 Establishment of an in vitro system to evaluate the therapeutic effect of the investigational drug on ulcerative colitis using human colonic organoids [PDF]

, 2019
Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Takayoshi Shirasaki, Satoshi Watanabe, Nobuhiro Katsukura, Tetsuya Nakamura, Mamoru Watanabe   +7 more
openalex   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids. [PDF]

Genes Dev
McNerney C, Santiago CP, Eldred KC, Glass I, Reh TA, Hernandez A, Blackshaw S, Lord ND, Johnston RJ.   +8 more
europepmc   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Mastering Organoid Growth: A Complete Guide to Overcoming Methodological Challenges. [PDF]

MedComm (2020)
Jiao C, Karakaya OF, Dadgar N, Wehrle CJ, Massoud Z, Hong H, Fairchild RL, Leipzig N, Aucejo F, Ma WW, Melenhorst JJ, Gonzales SF, Schlegel A.   +12 more
europepmc   +1 more source

Notch signaling pathway inhibition in the specification of human retinal ganglion cells from induced pluripotent stem cell derived retinal organoids

, 2019
Zenith Acosta Torres, Tanya T. Kelley, Stephan C. Schürer, Daniel Pelaez   +3 more
openalex   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source