Results 231 to 240 of about 94,019 (259)

TWEAK/Fn14 Signaling Modulates Goblet Cell-Associated Mucin Responses in Mouse Small Intestinal Epithelial Organoids. [PDF]

Cells
Tamaki S, Kono M, Arikawa S, Higashi Y, Maekawa T, Hara Y, Tsujimoto T, Kawakami F, Imai M, Kurosaki Y, Naito S, Ishii N, Ichikawa T, Kawashima R.   +13 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

Modelling ischaemic AKI in human kidney organoids reveals injury-associated epithelial states and macrophage-epithelial crosstalk. [PDF]

Genome Med
Nunez-Nescolarde AB, Liao Y, Perlaza-Jiménez L, Piran M, Cheng Z, Barlow CK, Steele JR, Deveson D, Moreau JLM, Lee HC, Li J, Schittenhelm RB, Wells CA, Shi W, Nikolic-Paterson DJ, Combes AN.   +15 more
europepmc   +1 more source

The sixth sense of the brain: interoception in organoid study. [PDF]

Bone Res
Li J, Wang F, Gao Q, Chen X, Bai L, Su J.   +5 more
europepmc   +1 more source

Organoid Intelligent Morphomics: Decoding the organoid morphome through artificial intelligence from phenotypic quantification to mechanistic insight. [PDF]

Bioact Mater
Li S, Huang J, Yan Y, Jaspers RT, Pathak JL, Xiao Y, Zhang Q.   +6 more
europepmc   +1 more source

Organoids as an emerging platform for osteoarthritis drug development. [PDF]

Clin Transl Med
Lyu X, Wang J, Su J.
europepmc   +1 more source

Modeling reptile virus infection in vitro using Python regius airway organoids. [PDF]

Nat Commun
Willemsen S, van Son G, Rissmann M, Akkerman N, Begthel H, Korving J, Ammerlaan C, Haagmans BL, van Es J, Clevers H.   +9 more
europepmc   +1 more source

IL-22 increases proglucagon-expressing enteroendocrine cells via STAT3 in human iPSC-derived intestinal epithelium.

Endocrinology
Inoue Y, Hattori K, Hamaguchi T, Sueki Y, Wakabayashi J, Funatsu Y, Watanabe H.   +6 more
europepmc   +1 more source

Engineered organoids for biomedical applications

Advanced Drug Delivery Reviews, 2023
As miniaturized and simplified stem cell-derived 3D organ-like structures, organoids are rapidly emerging as powerful tools for biomedical applications.
Ali Khademhosseini
exaly   +2 more sources