Results 31 to 40 of about 87,905 (291)

Role of the Calcium Plateau in the Neuronal Injury and Behavioral Morbidities Following Organophosphate Intoxication [PDF]

, 2016
Organophosphate (OP) chemicals include nerve agents and pesticides, and there is a growing concern of OP based chemical attacks against civilians. Current antidotes are essential in limiting immediate mortality associated with OP exposure.
Battaglia F.P., Campbell S., Dingeman A., Filbert M., Karki P., Konradsen F., Moorcraft P., Than K., Yamashita M.   +8 more
core   +2 more sources

Plasma Cholinesterase Levels of Nepalese Farmers Following Exposure to Organophosphate Pesticides

Environmental Health Insights, 2017
Background: Farmers in developing countries use highly toxic organophosphate pesticides. Thus, the aim of this study was to compare plasma cholinesterase (PChE) enzyme activity before and after exposure to organophosphate pesticides in a real-life ...
Dinesh Neupane, Erik Jørs, Lars Peter Andreas Brandt   +2 more
doaj   +1 more source

Pharmacological Blockade of the Calcium Plateau Provides Neuroprotection Following Organophosphate Paraoxon Induced Status Epilepticus in Rats [PDF]

, 2016
Organophosphate (OP) compounds which include nerve agents and pesticides are considered chemical threat agents. Currently approved antidotes are crucial in limiting OP mediated acute mortality.
Ajdacic-Gross, Bajgar, Baker, Barkus, Battaglia, Bengtson, Beverly A. Huang, Campbell, Chemical Hazards Emergency Medical Management, de Araujo Furtado, DeLorenzo, DeLorenzo, Deshpande, Deshpande, Deshpande, Deshpande, Deshpande, Faure, Filbert, Grynkiewicz, Haley, Helmstaedter, Hood, Konradsen, Kristin F. Phillips, Laxmikant S. Deshpande, Li, Li, Loubinoux, Nagarkatti, Neligan, Niebauer, Peng, Phillips, Raghupathi, Raza, Robert E. Blair, Robert J. DeLorenzo, Rod, Savage, Sellstrom, Than, Truitt, Tuovinen   +43 more
core   +2 more sources

Signatures of Insecticide Selection in the Genome of Drosophila melanogaster

G3: Genes, Genomes, Genetics, 2018
Resistance to insecticides has evolved in multiple insect species, leading to increased application rates and even control failures. Understanding the genetic basis of insecticide resistance is fundamental for mitigating its impact on crop production and
David Duneau, Haina Sun, Jonathan Revah, Keri San Miguel, Henry D. Kunerth, Ian V. Caldas, Philipp W. Messer, Jeffrey G. Scott, Nicolas Buchon   +8 more
doaj   +1 more source

Multiple Small Intestine Perforations after Organophosphorous Poisoning: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2016
Organophosphate poisoning has significant gastrointestinal manifestations including vomiting, diarrhea, cramps and increased salivation. We report an uncommon gastrointestinal complication of multiple small intestinal perforations following ...
Rubina Khullar Mahajan, Sudha Jasmine Rajan, John Victor Peter, Mayur Keshav Suryawanshi   +3 more
doaj   +1 more source

Transcriptional Profiles for Glutamate Transporters Reveal Differences Between Organophosphates but Similarities with Unrelated Neurotoxicants [PDF]

, 2010
The developmental neurotoxicity of organophosphates involves mechanisms other than their shared property as cholinesterase inhibitors, among which are excitotoxicity and oxidative stress.
Lobner, Doug, Seidler, Frederic J., Slotkin, Theodore A.   +2 more
core   +2 more sources

A Review of a Class of Emerging Contaminants: The Classification, Distribution, Intensity of Consumption, Synthesis Routes, Environmental Effects and Expectation of Pollution Abatement to Organophosphate Flame Retardants (OPFRs)

International Journal of Molecular Sciences, 2019
Organophosphate flame retardants (OPFRs) have been detected in various environmental matrices and have been identified as emerging contaminants (EC). Given the adverse influence of OPFRs, many researchers have focused on the absorption, bioaccumulation ...
Jiawen Yang, Yuanyuan Zhao, Minghao Li, Meijin Du, Xixi Li, Yu Li   +5 more
semanticscholar   +1 more source

Organophosphate Esters in the Canadian Arctic Ocean.

Environmental Science and Technology, 2020
Eleven organophosphate esters (OPEs) were detected in surface water and sediment samples from yearly sampling (2013-2018) in the Canadian Arctic. In water samples, ∑chlorinated-OPEs (Cl-OPEs) concentrations exceeded ∑non-chlorinated-OPEs (non-Cl-OPEs ...
R. Sühring, M. Diamond, S. Bernstein, Jennifer K. Adams, Jasmin K. Schuster, K. Fernie, K. Elliott, G. Stern, L. Jantunen   +8 more
semanticscholar   +1 more source

Evaluation of acetylcholine esterase activity in the blood of workers exposed [PDF]

Kirkuk Journal of Science, 2013
Introduction:Organophosphate and carbamate insecticides pose major environmental pollution problems and health hazards to people and animals. These insecticides inhibit cholinesterase (ChE) activity in the nervous tissues and neuromuscular junctions.
Aydin S. Ahmed
doaj   +1 more source

Unlocking Lactonase Enzymes as Biocatalysts for the Deracemisation of Chiral γ‐Thiolactones

Angewandte Chemie, EarlyView.
The application of lactonase enzymes as biocatalysts still remains underexplored. This study discloses the biocatalytic activity of two lactonases in the deracemisation of chiral C3‐substituted‐γ‐thiolactones. The biocatalyst GcL catalyses the enzymatic kinetic resolution (EKR) of C3‐amide‐thiolactones, while the rationally engineered biocatalyst N9 ...
Jingyue Wu, Michele Crotti, Ivan Bassanini, Mahdi Hassankalhori, Erica Elisa Ferrandi, Ferran Sancho, Daniela Monti, Daniele Castagnolo   +7 more
wiley   +2 more sources