Results 11 to 20 of about 15,415 (237)

Transitioning from Oxime to the Next Potential Organophosphorus Poisoning Therapy Using Enzymes

Journal of Chemistry, 2021
For years, organophosphorus poisoning has been a major concern of health problems throughout the world. An estimated 200,000 acute pesticide poisoning deaths occur each year, many in developing countries.
Rauda A. Mohamed, Keat K. Ong, Noor Azilah M. Kasim, Norhana A. Halim, Siti Aminah M. Noor, Victor F. Knight, Nurul Najwa Ab. Rahman, Wan Md Zin W. Yunus   +7 more
doaj   +1 more source

Chemical Weapons: History of the Study of Organophosphorus Toxic Agents Abroad

Вестник войск РХБ защиты, 2023
Organophosphorus compounds occupy a unique positon among all chemical warfare agents (CWA's). Since the 1930-s their high toxicity, wide range of physical-chemical properties and complex action attracted close attention of foreign military experts.
I. A. Nelga, I. V. Medvetsky, A. V. Zlobin, S. V. Tretyakov, A. V. Sherstyuk, I. V. Kostyuchenko   +5 more
doaj   +1 more source

Development of a Larval Zebrafish Model for Acute Organophosphorus Nerve Agent and Pesticide Exposure and Therapeutic Evaluation

Toxics, 2020
Organophosphorus compound exposure remains a present threat through agricultural accidents, warfare, or terrorist activity. The primary mechanism of organophosphorus toxicity is through inhibition of the enzyme acetylcholinesterase, with current ...
Jeffrey A. Koenig, Cindy Acon Chen, Tsung-Ming Shih   +2 more
doaj   +1 more source

Chemistry, Metabolism and Neurotoxicity of Organophosphorus Insecticides: A Review [PDF]

Nature Environment and Pollution Technology, 2023
Organophosphorus compounds (OPs) are phosphoric acid derivatives represented by the formula (R2XP=O/S), R as organic groups; however, they need not contain a direct carbon-phosphorus bond.
Ashutosh Singh, Abhishek Singh, Akhilesh Singh, Priti Singh, Vivek Singh, Yogender Singh, Hardeep Singh Tuli, Hadi Sajid Abdulabbas and Abhishek Chauhan
doaj   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante   +14 more
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Organocatalytic asymmetric synthesis of P-stereogenic molecules

Frontiers in Chemistry, 2023
P-chirality broadly appears in natural and synthetic functional molecules. The catalytic synthesis of organophosphorus compounds bearing P-stereogenic centers is still challenging, due to the lack of efficient catalytic systems.
Junyang Liu, Junyang Liu, Hang Chen, Min Wang, Wangjin He, Jia-Lei Yan   +5 more
doaj   +1 more source

Chemistry of Phosphorylated Formaldehyde Derivatives. Part I

Molecules, 2014
The underinvestigated derivatives of unstable phosphorylated formaldehyde acetals and some of the structurally related compounds, such as thioacetals, aminonitriles, aminomethylphosphinoyl compounds, are considered.
Vasily P. Morgalyuk
doaj   +1 more source

Flame Retardant Compounds for Epoxy Resins: A Review [PDF]

علوم و تکنولوژی پلیمر, 2021
Epoxy resins are widely used as encapsulating materials in the electronic and electrical industries, transportation, coatings, adhesives, and advanced composite matrices owing to their excellent heat, moisture and chemical resistance, high tensile ...
Jamshid Kamalipour, Mohammad Hosain Beheshty, Mohamad Jalaledin Zohuriaan-Mehr   +2 more
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Compostos organofosforados pentavalentes: histórico, métodos sintéticos de preparação e aplicações como inseticidas e agentes antitumorais Organophosphorus pentavalent compounds: history, synthetic methods of preparation and application as insecticides and antitumor agents

Química Nova, 2007
This paper is a review of the history, synthesis and application of organophosphorus compounds, especially of those of pentavalent phosphorus, such as phosphoramidates, phosphorothioates, phosphonates and phosphonic acids with insecticide and anticancer ...
Viviane Martins Rebello dos Santos, Claudio Luis Donnici, João Batista Neves DaCosta, Janaína Marques Rodrigues Caixeiro   +3 more
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Study on the Degradation Effect of Three Organophosphorus Hydrolase Mutant on Sarin [PDF]

E3S Web of Conferences, 2021
Organophosphorus hydrolase can effectively degrade organic phosphorus compounds such as sarin. In this study, we constructed a recombinant Bacillus subtilis mutant expressing organophosphorus hydrolase, measured the effect of the mutant on the ...
Gu Qiamin, Zhao Chuanxin, Xi Hailing, Liu Min, Chen Gaoyun   +4 more
doaj   +1 more source