Orientia tsutsugamushi in Eschars from Scrub Typhus Patients [PDF]
Emerging Infectious Diseases, 2006 To verify the value of eschars for the diagnosis of scrub typhus and to characterize genotypes of Orientia tsutsugamushi in patients, we examined eschars and blood specimens of 7 patients from Shandong Province, People's Republic of China, for O ...
Yun-Xi Liu +6 more
doaj +5 more sources
Orientia tsutsugamushi: A life between escapes. [PDF]
Microbiologyopen, 2023 Intracellular bacteria have evolved different strategies to invade, replicate and persist in, and eventually exit from their hosts. The life cycle of the mite-borne, obligate intracellular pathogen Orientia tsutsugamushi (Ot), the causative agent of human scrub typhus, differs in many aspects from that of other members of the Rickettsiales order ...
Fromm L, Mehl J, Keller C.
europepmc +5 more sources
Antigenic Relationships among Human Pathogenic Orientia tsutsugamushi Isolates from Thailand. [PDF]
PLoS Neglected Tropical Diseases, 2016 BackgroundScrub typhus is a common cause of undiagnosed febrile illness in certain tropical regions, but can be easily treated with antibiotics. The causative agent, Orientia tsutsugamushi, is antigenically variable which complicates diagnosis and ...
Sarah L James +6 more
doaj +4 more sources
Intracellular invasion of Orientia tsutsugamushi activates inflammasome in asc-dependent manner. [PDF]
PLoS ONE, 2012 Orientia tsutsugamushi, a causative agent of scrub typhus, is an obligate intracellular bacterium, which escapes from the endo/phagosome and replicates in the host cytoplasm. O.
Jung-Eun Koo +4 more
doaj +6 more sources
Orientia tsutsugamushi Modulates RIPK3 Cellular Levels but Does Not Inhibit Necroptosis [PDF]
PathogensScrub typhus is an emerging chigger-borne disease caused by the obligate intracellular bacterium Orientia tsutsugamushi. Necroptosis is a form of programmed cell death (PCD) mediated by RIPK3 (serine/threonine kinase receptor interacting protein 3) and ...
Thomas E. Siff +6 more
doaj +2 more sources
Utility of next-generation sequencing for the etiological diagnosis of Orientia tsutsugamushi infection [PDF]
Infectious MedicineBackground: Scrub typhus, an acute febrile disease caused by Orientia tsutsugamushi, is transmitted to humans through infected chigger mites. We present a case of scrub typhus in a previously healthy man from Shandong Province diagnosed using next ...
Nannan Xu +4 more
doaj +2 more sources
Survival and Growth of Orientia tsutsugamushi in Conventional Hemocultures [PDF]
Emerging Infectious Diseases, 2016 Orientia tsutsugamushi, which requires specialized facilities for culture, is a substantial cause of disease in Asia. We demonstrate that O. tsutsugamushi numbers increased for up to 5 days in conventional hemocultures.
Sabine Dittrich +12 more
doaj +5 more sources
Orientia tsutsugamushi modulates p53, the cell cycle, and genotoxicity to maintain its intracellular niche [PDF]
Nature CommunicationsInfections by intracellular pathogens often cause insult to host cell DNA, which stimulates responses that ultimately eliminate the damaged cell and hence the microbial niche.
Paige E. Allen +3 more
doaj +2 more sources
Urine Metabolite of Mice with Orientia tsutsugamushi Infection. [PDF]
Am J Trop Med Hyg, 2023 ABSTRACT. Scrub typhus is an acute febrile, mite-borne disease endemic to the Asia–Pacific region. In South Korea, it is a seasonal disease that occurs frequently in the autumn, and its incidence has increased steadily. In this study, we used a liquid chromatography and flow injection analysis–tandem mass spectrometry-based targeted urine metabolomics ...
Choi S +7 more
europepmc +3 more sources
Rare Coinfection of Scrub Typhus and Malaria in Immunocompetent Person [PDF]
Online Journal of Health & Allied Sciences, 2012 Scrub Typhus, or tsutsugamushi disease is a febrile illness caused by bacteria of the family Rickettsiaceae and named Orientia tsutsugamushi. Recently it has been found to endemic in Subhimalayan region of India.Malaria is highly endemic in rest of India
Ashok Sharma +5 more
doaj +2 more sources