Results 21 to 30 of about 5,617 (192)
Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression [PDF]
Nature CommunicationsHow intracellular bacteria subvert the major histocompatibility complex (MHC) class I pathway is poorly understood. Here, we show that the obligate intracellular bacterium Orientia tsutsugamushi uses its effector protein, Ank5, to inhibit nuclear ...
Haley E. Adcox +6 more
doaj +2 more sources
Differences in clinical features according to Boryoung and Karp genotypes of Orientia tsutsugamushi. [PDF]
PLoS ONE, 2011 Scrub typhus is an infectious disease caused by Orientia tsutsugamushi. The differences in virulence of O. tsutsugamushi prototypes in humans are still unknown.
Dong-Min Kim +10 more
doaj +5 more sources
Orientia tsutsugamushi: A life between escapes. [PDF]
Microbiologyopen, 2023 Intracellular bacteria have evolved different strategies to invade, replicate and persist in, and eventually exit from their hosts. The life cycle of the mite-borne, obligate intracellular pathogen Orientia tsutsugamushi (Ot), the causative agent of human scrub typhus, differs in many aspects from that of other members of the Rickettsiales order ...
Fromm L, Mehl J, Keller C.
europepmc +5 more sources
Orientia tsutsugamushi, the agent of scrub typhus
WikiJournal of Medicine, 2019 Orientia tsutsugamushi is a mite-borne bacterium belonging to the family Rickettsiaceae and is responsible for the disease scrub typhus in humans. It is an obligate intracellular parasite of trombiculid mites, in which natural transmission is maintained ...
Kholhring Lalchhandama
doaj +2 more sources
Molecular Epidemiology and Genetic Diversity of Orientia tsutsugamushi From Patients and Small Mammals in Xiangyun County, Yunnan Province, China. [PDF]
Vet Med SciScrub typhus is caused by Orientia tsutsugamushi (OT). In this study, the detection rates of OT in patients and small mammals were 28.13% (18/64) and 13.98% (13/93), respectively. Nine full‐length 56‐kDa TSA genes were identified, comprising four distinct genotypes: Karp‐like (n = 3), Kato‐like (n = 3), Gilliam (n = 2), and TA763 (n = 1). Recombination
Chen L +9 more
europepmc +2 more sources
Genetic Characterization of Orientia tsutsugamushi, Bhutan, 2015. [PDF]
Emerg Infect DisTshokey T +4 more
europepmc +3 more sources
Analysis of Orientia tsutsugamushi promoter activity [PDF]
Pathogens and Disease, 2021 ABSTRACT Orientia tsutsugamushi is an obligate intracellular bacterium that causes scrub typhus, a potentially fatal rickettsiosis, and for which no genetic tools exist. Critical to addressing this technical gap is to identify promoters for driving expression of antibiotic resistance and fluorescence reporter genes in O.
Jason R Hunt, Jason A Carlyon
openaire +2 more sources
Shotgun proteomics of Orientia tsutsugamushi [PDF]
Clinical Microbiology and Infection, 2009 Orientia tsutsugamushi is one of the obligate intracellular bacteria, and causes Tsutsugamushi disease (scrub typhus). The whole genome sequence of Boryong strain revealed some characteristics of this bacterium, such as a type IV secretion system, many histidine kinases, SpoT, Tra, and ankyrin repeatand tetratricopeptide repeat (TPR)-containing ...
Ogawa, M. +7 more
openaire +2 more sources
Urine Metabolite of Mice with Orientia tsutsugamushi Infection. [PDF]
Am J Trop Med Hyg, 2023 ABSTRACT. Scrub typhus is an acute febrile, mite-borne disease endemic to the Asia–Pacific region. In South Korea, it is a seasonal disease that occurs frequently in the autumn, and its incidence has increased steadily. In this study, we used a liquid chromatography and flow injection analysis–tandem mass spectrometry-based targeted urine metabolomics ...
Choi S +7 more
europepmc +3 more sources