Results 201 to 210 of about 569,837 (343)

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Site-specific ORC binding, pre-replication complex assembly and DNA synthesis at Schizosaccharomyces pombe replication origins

, 2002
Dong Kong
openalex   +1 more source

Choosing a suitable method for the identification of replication origins in microbial genomes [PDF]

, 2015
Chengcheng Song, Shaocun Zhang, He Huang
openalex   +1 more source

The DNA replication initiation protein DnaD is recruited to a specific strand of the Bacillus subtilis chromosome origin

, 2022
Charles Winterhalter, Simone Pelliciari, Daniel Stevens, Stepan Fenyk, Elie Marchand, Nora Cronin, Panos Soultanas, Tiago R. D. Costa, Aravindan Ilangovan, Heath Murray   +9 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Genetic mapping of the chromosomal replication origin of Salmonella typhimurium [PDF]

, 1979
Kei-Ichiro Joh, S Hiraga
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Inter-origin cooperativity of geminin action establishes an all-or-none switch for replication origin licensing [PDF]

, 2011
Koji L. Ode, Koichi Fujimoto, Yumiko Kubota, Haruhiko Takisawa   +3 more
openalex   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

Effects of the pSC101 partition (par) locus onin vivoDNA supercoiling near the plasmid replication origin [PDF]

, 1995
Deirdre L. Conley, Stanley N. Cohen
openalex   +1 more source