Results 261 to 270 of about 587,545 (300)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Loss of G1-phase CDK-inhibition biases instability between genomic regions by unevenly reducing activity among replication origins. [PDF]

iScience
Gomes F, Devesa F, Ayuda-Durán P, Aza P, Agote-Arán A, Cavero D, Embarc-Buh A, González A, Bermejo R, Calzada A.   +9 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

The Escherichia coli replication initiator DnaA is titrated on the chromosome. [PDF]

Nat Commun
Olivi L, Köstlbacher S, Ludwig C, Langendoen M, Claassens NJ, Ettema TJG, van der Oost J, Ten Wolde PR, Hohlbein J, Staals RHJ.   +9 more
europepmc   +1 more source

Detecting Dengue in Flight: Leveraging Machine Learning to Analyze Mosquito Flight Patterns for Infection Detection

Advanced Biology, EarlyView.
Dengue infection alters mosquito flight behavior, enabling detection using machine learning classifiers. This study analyzes 3D flight trajectories and evaluates multiple models, showing that longer sequence lengths improve classification performance.
Nouman Javed, Adam J. López‐Denman, Prasad N. Paradkar, Asim Bhatti   +3 more
wiley   +1 more source

Compact Origins and Where to Find Them: ORC's Guide to Genome-Wide Licensing. [PDF]

Bioessays
Speck C, Reuter LM.
europepmc   +1 more source

DNA replication timing reveals genome-wide features of transcription and fragility. [PDF]

Nat Commun
Berkemeier F, Cook PR, Boemo MA.
europepmc   +1 more source

Emerging <i>in vitro</i> models to study Merkel cell carcinoma pathobiology. [PDF]

Front Cell Dev Biol
Mazziotta C, Rotondo JC.
europepmc   +1 more source

Deciphering the Replication-Division Coordination in E. coli: A Unified Mathematical framework for Systematic Model Comparison

Perrin A, Doumic M, El Karoui M, Méléard S.   +3 more
europepmc   +1 more source

A novel gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types. [PDF]

Mol Ther Methods Clin Dev
Prince C, Bounoutas G, Zhou B, Raja W, Gold I, Pozsgai R, Thakker P, Boisvert N, Reardon C, Thurmond S, Ozturk E, Boggavarapu R, Johnson JA, Jeraldo P, Springer S, Chahal L, Stead E, Dodier C, Vought B, Nogalski M, Nawandar D, Wright C, Mackey A, Parsons G, Cabral J.   +24 more
europepmc   +1 more source