Results 301 to 310 of about 569,837 (343)

Cybernetic origins of replication

Origins of life and evolution of the biosphere, 1988
An evolutionary progression leading toward replication is resolved into several phases; (a) the replication of RNA segments by self-priming and -templating, (b) the replication of single stranded molecules by elongation and controlled scission, (c) replication of complementary duplexes and (d) replication of DNA.
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The replication origin of Azotobacter vinelandii

Molecular and General Genetics MGG, 2000
The putative replication origin of Azotobacter vinelandii was cloned as an autonomously replicating fragment after ligation to an antibiotic resistance cartridge. The resulting plasmids could be isolated and labelled by Southern hybridisation with the antibiotic resistance cartridge as probe and also visualised by electron microscopy.
R A, Singh, N R, Choudhury, H K, Das
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The regulation of replication origin activation

Current Opinion in Genetics & Development, 1999
At the start of the cell-division programme, proteins must be assembled onto replication origins to establish competence for initiation of DNA synthesis. At the correct moment, other effectors must then coordinate appropriate firing of the various origins to control entry into and progress through S phase.
Donaldson, Anne D., Blow, J. Julian
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A Replication Origin of Bacillus thuringiensis

Current Microbiology, 2000
A replication origin of Bacillus thuringiensis (Bt) was found in a Bacillus thuringiensis-Escherichia coli shuttle vector of pHT3101. Deletion analysis showed that the replication origin was segregationally stable at suitable temperature for Bt growth. The fragment containing the replication origin was cloned in pUC18 and sequenced.
J, Yu, Y, Zhang, Y, Pang, M, Xu
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Cancer: Involvement of replicative origins?

Medical Hypotheses, 1986
The assumption is made that movable genetic elements related to cancer are replicons and/or replicative origins. Some evidence is provided that certain mobile Alu-origins may represent candidates for precursors of chromosomal insertions. They could incorporate and interact with "fixed" chromosomal origins converting them to "procaryotic" ones. In other
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Multiple origins of replication in archaea

Trends in Microbiology, 2004
Until recently, the only archaeon for which a bona fide origin of replication was reported was Pyrococcus abyssi, where a single origin was identified. Although several in silico analyses have suggested that some archaeal species might contain more than one origin, this has only been demonstrated recently.
Lori M, Kelman, Zvi, Kelman
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Licensing of Replication Origins

2016
All living organisms need to duplicate their genetic material prior to cell division in order to maintain genomic-stability. Cells have evolved sophisticated DNA replication mechanisms to ensure that this process is as faithful as possible. Eukaryotic initiation of DNA replication is a two-step process, where the replicative DNA helicase becomes loaded
Alberto Riera, Christian Speck
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Origins of replication and gene regulation

Molecular and Cellular Biochemistry, 1984
Eukaryotic chromosomes appear to consist of many replicons, the time of replication of which is probably controlled by specific origins. However, plasmids without specific eukaryotic origins may also replicate in some cells when injected into nuclei or transferred during transformation.
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The Origin of Adenovirus DNA Replication

1983
Current efforts to understand regulation of replication and cell growth often focus on initiation of DNA replication at an origin sequence. It is most likely, although not yet proven in eukaryotes, that the ultimate step in the regulation of the G to S transition in the cell cycle is the priming of DNA synthesis at an origin.
Tamanoi, F., Stillman, B. W.
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On the origin of bacteriophage ∅X174 replicative form DNA replication

Virology, 1976
Abstract The origin of RF DNA replication of ∅X174, as identified by the method of repair of heteroduplex DNA ( Baas and Jansz, 1972 ), has been mapped more accurately, within gene A. Heteroduplexes of the wild-type minus strand and the plus (viral) strand of several well-localized gene A amber mutants were used to infect permissive spheroplasts ...
P J, Weisbeek, G A, Van Arkel
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