Results 311 to 320 of about 569,837 (343)
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Origins of Chromosome Replication

1998
The first obligatory step for replication of duplex DNA is strand separation. Duplex melting (unwinding) leading to initiation of bacterial chromosome replication normally occurs at a fixed site on the chromosome termed oriC. This local duplex unwinding is effected by specific binding of an initiator, DnaA protein encoded by the dnaA gene, to 9-bp ...
openaire   +1 more source

EUKARYOTIC DNA REPLICATION: Anatomy of An Origin

Annual Review of Biochemistry, 1993
PERSPECTIVE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 ORIGINS OF DNA REPLICATION IN SIMPLE GENOMES . . . . . . . . . . . . . . . 31 Functional and Genetic Origins Are Coincident . . . . . . . . . . . . . . . . . . . . .
openaire   +2 more sources

Replication origin plasticity, Taylor-made: inhibition vs recruitment of origins under conditions of replication stress

Chromosoma, 2007
Among his many contributions to the field of chromosome structure and dynamics, J. Herbert Taylor showed that eukaryotic cells have many more potential replication origins than they use, which they can recruit when replication forks are slowed to complete S-phase in a timely fashion.
openaire   +2 more sources

Eukaryotic Origins of DNA Replication

1993
Initiation of DNA replication acts as a failsafe point in the cell proliferation cycle, because it is a commitment to cell division and, therefore, central to control of the eukaryotic cell cycle (Laskey et al. 1989). In addition, initiation of DNA replication is coupled to programmed changes in gene expression that occur during the life of a single ...
M. L. DePamphilis   +3 more
openaire   +1 more source

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino   +2 more
exaly  

Origin of replication of Thermotoga maritima

Trends in Genetics, 2000
P, Lopez   +3 more
openaire   +2 more sources

Origin and regulation of oxygen redox instability in high-voltage battery cathodes

Nature Energy, 2022
Xiang Liu   +2 more
exaly  

The current state of molecular testing in the treatment of patients with solid tumors, 2019

Ca-A Cancer Journal for Clinicians, 2019
Wafik S El-Deiry   +2 more
exaly  

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