Results 51 to 60 of about 598,816 (344)
The dynamics of replication licensing in live Caenorhabditis elegans embryos [PDF]
, 2012 Accurate DNA replication requires proper regulation of replication licensing, which entails loading MCM-2-7 onto replication origins. In this paper, we provide the first comprehensive view of replication licensing in vivo, using video microscopy of ...
Anton Gartner +56 more
core +4 more sources
Viruses, 2020 Lactococcus Ceduovirus (formerly c2virus) bacteriophages are among the three most prevalent phage types reported in dairy environments. Phages from this group conduct a strictly lytic lifestyle and cause substantial losses during milk fermentation ...
Magdalena Chmielewska-Jeznach +2 more
doaj +1 more source
Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation [PDF]
, 1989 A cell-free DNA replication system dependent upon five purified cellular proteins, one crude cellular fraction, and the simian virus 40 (SV40)-encoded large tumor antigen (T antigen) initiated and completed replication of plasmids containing the SV40 ...
Tsurimoto, T. +2 more
core +1 more source
The epigenetic control of E-box and Myc-dependent chromatin modifications regulate the licensing of lamin B2 origin during cell cycle [PDF]
, 2012 Recent genome-wide mapping of the mammalian replication origins has suggested the role of transcriptional regulatory elements in origin activation. However, the nature of chromatin modifications associated with such trans-factors or epigenetic marks ...
Kumar, V, Singh, AK, Swarnalatha, M
core +1 more source
Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication [PDF]
, 2017 Gain-of-function (GOF) p53 mutations are observed frequently in most intractable human cancers and establish dependency for tumor maintenance and progression.
Beckerman +14 more
core +2 more sources
Journal of Biological Chemistry, 1988 Complexes previously identified in the reconstitution of stages in the initiation of replication of plasmids (oriC) bearing the origin of the Escherichia coli chromosome have been examined further.
K. Sekimizu, D. Bramhill, A. Kornberg
semanticscholar +1 more source
Metazoan DNA replication origins [PDF]
Current Opinion in Cell Biology, 2019 DNA replication starts with the opening of DNA at sites called DNA replication origins. From the single sequence-specific DNA replication origin of the small Escherichia coli genome, up to thousands of origins that are necessary to replicate the large human genome, strict sequence specificity has been lost.
Olivier, Ganier +3 more
openaire +2 more sources
Chromosome I controls chromosome II replication in Vibrio cholerae.
PLoS Genetics, 2014 Control of chromosome replication involves a common set of regulators in eukaryotes, whereas bacteria with divided genomes use chromosome-specific regulators. How bacterial chromosomes might communicate for replication is not known.
Jong Hwan Baek, Dhruba K Chattoraj
doaj +1 more source
The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator [PDF]
, 1993 The bovine papillomavirus type I transcriptional activator E2 is essential for replication of bovine papillomavirus DNA, yet most of the high-affinity binding sites for E2 are dispensable.
Ustav, E. +3 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source