Results 231 to 240 of about 207,238 (265)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Characterization of a Goose-Origin Avian Orthoreovirus with Interferon Suppression Activity. [PDF]

open access: yesViruses
Liu Y   +10 more
europepmc   +1 more source

Structure of the origin recognition complex bound to DNA replication origin

open access: yesNature, 2018
The six-subunit origin recognition complex (ORC) binds to DNA to mark the site for the initiation of replication in eukaryotes. Here we report a 3 Å cryo-electron microscopy structure of the Saccharomyces cerevisiae ORC bound to a 72-base-pair origin DNA
Ningning Li   +2 more
exaly   +5 more sources

Coordinate Binding of ATP and Origin DNA Regulates the ATPase Activity of the Origin Recognition Complex

open access: yesCell, 1997
The Origin Recognition Complex (ORC) is a six-protein assembly that specifies the sites of DNA replication initiation in S. cerevisiae. Origin recognition by ORC requires ATP.
Stephen P Bell
exaly   +2 more sources

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