Results 291 to 300 of about 1,409,521 (314)

Yeast origin recognition complex functions in transcription silencing and DNA replication.

Science, 1993
The genes encoding two of the subunits of the Saccharomyces cerevisiae origin recognition complex (ORC) have been isolated. Characterization of a temperature-sensitive mutation in the gene encoding the 72-kD subunit of ORC ( ORC2 ) indicates that this protein complex functions early in the ...
S. Bell, R. Kobayashi, B. Stillman
semanticscholar   +3 more sources

A Drosophila Homolog of the Yeast Origin Recognition Complex

Science, 1995
Genes from Drosophila melanogaster have been identified that encode proteins homologous to Orc2p and Orc5p of the Saccharomyces cerevisiae origin recognition complex (ORC). The abundance of the Drosophila Orc2p homolog DmORC2 is developmentally regulated and is ...
M, Gossen, D T, Pak, S K, Hansen, J K, Acharya, M R, Botchan   +4 more
openaire   +2 more sources

Multiple Functions of the Origin Recognition Complex

2007
The origin recognition complex (ORC), a heteromeric six-subunit protein, is a central component for eukaryotic DNA replication. The ORC binds to DNA at replication origin sites in an ATP-dependent manner and serves as a scaffold for the assembly of other key initiation factors. Sequence rules for ORC-DNA binding appear to vary widely.
openaire   +2 more sources

Replication Origin Recognition and Deformation by a Heterodimeric Archaeal Orc1 Complex

Science, 2007
The faithful duplication of genetic material depends on essential DNA replication initiation factors. Cellular initiators form higher-order assemblies on replication origins, using adenosine triphosphate (ATP) to locally remodel duplex DNA and facilitate proper loading of synthetic replisomal components.
Erin L Cunningham, Dueber, Jacob E, Corn, Stephen D, Bell, James M, Berger   +3 more
openaire   +2 more sources

Replication | DNA Replication: Eukaryotic Origins and the Origin Recognition Complex

2021
Igor Chesnokov, Katarina Akhmetova
openaire   +1 more source

Origin Recognition Complex

2011
openaire   +1 more source

Origin Recognition Complex

2006
openaire   +1 more source

Tumors of Peripheral Nerve Origin: Benign and Malignant Solitary Schwannomas

Ca-A Cancer Journal for Clinicians, 1970
Tapas K. Das Gupta
exaly  

ORC (origin recognition complex)

2008
openaire   +1 more source

Coordinate Binding of ATP and Origin DNA Regulates the ATPase Activity of the Origin Recognition Complex

Cell, 1997
Stephen P Bell
exaly