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The algorithmic origins of life [PDF]
Journal of The Royal Society Interface, 2013 Although it has been notoriously difficult to pin down precisely what is it that makes life so distinctive and remarkable, there is general agreement that its informational aspect is one key property, perhaps the key property. The unique informational narrative of living systems suggests that life may be characterized by context-dependent causal ...
Walker, Sara Imari, Davies, Paul C. W.
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Quantifying the origins of life on a planetary scale. [PDF]
Proc Natl Acad Sci U S A, 2016 Significance In this paper, we describe an equation to estimate the frequency of planetary “origin of life”-type events that is similar in intent to the Drake Equation but with some key advantages—specifically, our formulation makes an explicit ...
Scharf C, Cronin L.
europepmc +7 more sources
Origins of Life: The Protein Folding Problem all over again? [PDF]
Proc Natl Acad Sci U S AHow did specific useful protein sequences arise from simpler molecules at the origin of life? This seemingly needle-in-a-haystack problem has remarkably close resemblance to the old Protein Folding Problem, for which the solution is now known from ...
Kocher CD, Dill KA.
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Membraneless polyester microdroplets as primordial compartments at the origins of life. [PDF]
Proc Natl Acad Sci U S A, 2019 Significance The prebiotic milieu was likely heterogeneous, consisting of a large number of chemicals and their associated reactions, including those not only of biological compounds, but also nonbiological compounds.
Jia TZ +6 more
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Sequencing the origins of life [PDF]
BBA Advances, 2022 One goal of origins of life research is to understand how primitive informational and catalytic biopolymers emerged and evolved. Recently, a number of sequencing techniques have been applied to analysis of replicating and evolving primitive biopolymer ...
Tony Z. Jia +2 more
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Synthesis and Characterization of Amino Acid Decyl Esters as Early Membranes for the Origins of Life [PDF]
Membranes, 2022 Understanding how membrane forming amphiphiles are synthesized and aggregate in prebiotic settings is required for understanding the origins of life on Earth 4 billion years ago.
Isabella Lago +3 more
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A Chemist's Perspective on the Role of Phosphorus at the Origins of Life. [PDF]
Life (Basel), 2017 The central role that phosphates play in biological systems, suggests they also played an important role in the emergence of life on Earth. In recent years, numerous important advances have been made towards understanding the influence that phosphates ...
Fernández-García C +2 more
europepmc +2 more sources
Chance, necessity and the origins of life: a physical sciences perspective. [PDF]
Philos Trans A Math Phys Eng Sci, 2017 Earth's 4.5-billion-year history has witnessed a complex sequence of high-probability chemical and physical processes, as well as ‘frozen accidents’.
Hazen RM.
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A Strategy for Origins of Life Research. [PDF]
Astrobiology, 2015 Contents 1. Introduction 1.1. A workshop and this document 1.2. Framing origins of life science 1.2.1. What do we mean by the origins of life (OoL)? 1.2.2. Defining life 1.2.3. How should we characterize approaches to OoL science? 1.2.4. One path to life
Scharf C +36 more
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Life’s Late Digital Revolution and Why It Matters for the Study of the Origins of Life [PDF]
Life, 2017 The information contained in life exists in two forms, analog and digital. Analog information is manifest mainly in the differing concentrations of chemicals that get passed from generation to generation and can vary from cell to cell.
David A. Baum, Niles Lehman
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