Results 71 to 80 of about 10,116 (169)

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

Obesity, Volume 34, Issue 3, Page 565-578, March 2026.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden, Maria A. Oquendo, Robert F. Kushner, Dachuang Cao, Chrisanthi A. Karanikas, Afton Kechter, Madhumita A. Murphy   +6 more
wiley   +1 more source

Dynamics of lipid profile and circadian pressure rhythms in patients with obesity and arterial hypertension, treated with orlistat and its combination with ACE inhibitors

Кардиоваскулярная терапия и профилактика, 2005
Aim. To assess effects of orlistat and its combimation with enalapril on main cardiovascular risk parameters in young patients with obesity and arterial hypertension. Material and methods.
A. G. Avtandilov, A. S. Ametov, A. K. Ausheva, A. K. Bolotseva   +3 more
doaj  

Burden of long‐term conditions and management of people with overweight and obesity: Data from the United Kingdom primary care cohort of the IMPACT‐O study

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 1683-1692, March 2026.
Abstract Aims The multi‐country epIdeMiology landscape PAtient Care paThways of Obesity (IMPACT‐O) retrospective cohort study utilised existing electronic medical records to gather data on overweight and obesity. We report UK data on obesity‐related complications (ORCs) and management strategies.
Kamlesh Khunti, Matt Capehorn, Esther Artime, Lill‐Brith von Arx, Alun L. Davies, Atif Adam, Anastasia Lampropoulou   +6 more
wiley   +1 more source

Semaglutide and tirzepatide effects on cardiovascular outcomes in people with overweight or obesity in the real world (STEER)

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2403-2415, March 2026.
Abstract Aims To assess the real‐world effectiveness of semaglutide versus tirzepatide in reducing major adverse cardiovascular events (MACE) among patients with overweight/obesity and established atherosclerotic cardiovascular disease (ASCVD) without diabetes in an insured US population.
Lauren Wilson, Zhenxiang Zhao, Victoria Divino, Matthew Bassan, Bríain Ó. Hartaigh, Signe Stensen, Kerem Ozer   +6 more
wiley   +1 more source

Evaluation of gut microbiota alterations following orlistat administration in obese mice

Frontiers in Endocrinology
BackgroundThe gut microbiota plays a pivotal role in various metabolic disorders. Orlistat has shown beneficial effects on weight loss and metabolism, but its direct impact on the gut microbiota has not been extensively reported.
Chang Xue, Tianying Wang, Yang Chen, He Zhang, Hongjie Wang, Qiang Li   +5 more
doaj   +1 more source

Metaphorical investigation of aqueous distillate of Cichorium intybus, Foeniculum vulgare and Solanum nigrum along with atorvastatin and orlistat in experimental rodent models of dyslipidaemia and obesity

, 2023
Rufaida Wasim, Tarique Mahmood, Arshiya Shamim, Farogh Ahsan, Aditya Singh   +4 more
openalex   +1 more source

Effect of orlistat on periostin, adiponectin, inflammatory markers and ultrasound grades of fatty liver in obese NAFLD patients

Therapeutics and Clinical Risk Management, 2017
Rashid Ali Khan,1 Prem Kapur,2 Abhinav Jain,3 Farrukh Farah,4 Uma Bhandari11Department of Pharmacology, Faculty of Pharmacy, 2Department of Medicine, 3Department of Radiology, 4Department of Paramedical Sciences, Hamdard Institute of Medical Sciences ...
Ali Khan R, Kapur P, Jain A, Farah F, Bhandari U   +4 more
doaj  

Systematic review of the clinical efficacy of sibutramine and orlistat in weigth loss, quality of life and its adverse effects in obese adolescents Revisión sistemática sobre la eficacia clínica de la sibutramina y el orlistat en la pérdida de peso, calidad de vida y sus efectos adversos en obesos adolescentes

Nutrición Hospitalaria, 2011
Introduction: The prevalence of obesity, a serious public health problem, is increasing among teenagers and thus also increases cardiovascular morbidity and mortality in adulthood.
E. García Díaz, T. Martín Folgueras
doaj  

Changes in Plasma Leptin Levels in Men in Response to Aerobic Training, and Using Orlistat

مجله دانشکده پزشکی اصفهان, 2017
Background: Obesity is a complex disorder with excessive accumulation of adipose tissue; the tissue that exudes leptin, a hormone which plays an important role in the regulation of cellular metabolism and energy balance.
Abazar Teimoori, Farhad Rahmaninia, Bahman Mirzaie, Ramin Tajbakhsh   +3 more
doaj  

The combination of orlistat, lonidamine and 6‑diazo‑5‑oxo‑L‑norleucine induces a quiescent energetic phenotype and limits substrate flexibility in colon cancer cells

, 2020
Alejandro Schcolnik‐Cabrera, Alma Chávez‐Blanco, Guadalupe Domínguez-Gómez, Mandy Juárez, Donna Lai, Sheng Hua, Armando R. Tovar, José Díaz‐Chávez, Alfonso Dueñas‐González   +8 more
openalex   +2 more sources