Results 81 to 90 of about 50,539 (212)

Functional roles of ornithine decarboxylase and arginine decarboxylase during the peri-implantation period of pregnancy in sheep

Journal of Animal Science and Biotechnology, 2018
Background Polyamines stimulate DNA transcription and mRNA translation for protein synthesis in trophectoderm cells, as well as proliferation and migration of cells; therefore, they are essential for development and survival of conceptuses (embryo/fetus ...
Yasser Y. Lenis, Gregory A. Johnson, Xiaoqiu Wang, Wendy W. Tang, Kathrin A. Dunlap, M. Carey Satterfield, Guoyao Wu, Thomas R. Hansen, Fuller W. Bazer   +8 more
doaj   +1 more source

Differential effects of difluoromethylornithine on basal and induced activity of cerebral ornithine decarboxylase and mRNA [PDF]

, 1991
The induction of the activity of cerebral ornithine decarboxylase (EC 4.1.1.17) and mRNA by electrical stimulation exhibits regional differences. The effects of the enzyme inhibitor difluoromethylornithine on these regional variations was examined ...
Zawia, NH, Bondy, SC, Mattia, CJ
core   +1 more source

Testicular toll with viral intrusion: Molecular insights into the impact of chronic HIV infection on male fertility

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
The molecular mechanisms contributing to impaired fertility in HIV+ males remain poorly defined. Using a human immunodeficiency virus (HIV) transgenic (Tg) rat model, we demonstrate key structural and functional sperm regulators including cation channel of sperm (CatSper)1–4 channels and mitochondrial biogenesis genes were markedly downregulated ...
Tousif Ahmed Hediyal, Elizabeth M. Stone, Omar Shukri, Victoria L. Schaal, Amin Foroughi‐Nezhad, Murali Devanaboyina, Josef S. Crenshaw, Amir Elrefaie, Sree Kolli, Camryn N. Davis, Dinesh Pradhan, Sowmya V. Yelamanchili, Gurudutt Pendyala   +12 more
wiley   +1 more source

Ornithine decarboxylase and malignant growth

Bulletin of Experimental Biology and Medicine, 1993
There is indirect evidence that key enzymes which catalyse both synthesis and degradation of polyamines (PA) may be useful as biological markers of malignant growth. Ornithine decarboxylase (ODC) activity was assessed in fetal, regenerating and adult rat liver, in hepatoma with different growth rate, in Morris hepatoma cell lines and in rat liver in ...
openaire   +4 more sources

Satellite Glial Cells Synthesize and Release GABA to Activate Extrasynaptic GABAA Receptors That Modulate Dorsal Root Ganglia Neuron Excitability

Glia, Volume 74, Issue 9, September 2026.
Mechanism of synthesis, release, receptor activation, uptake, and degradation of GABA in dorsal root ganglia (DRG). Left: GABA is synthesized from putrescine in satellite glial cells (SGCs). After being released by Best1 channel, it activates GABAA receptors in sensory neurons, producing a chloride current.
Natalie Jiménez‐Barrios, Ricardo González‐Ramírez, Francisco Javier Paz‐Bermúdez, Guadalupe Raya‐Tafolla, José Segovia Vila, Ricardo Felix, Rodolfo Delgado‐Lezama, Benjamín Florán Garduño   +7 more
wiley   +1 more source

Irritable Bowel Disease: Think Malonic and Methylmalonic Aciduria (CMAMMA)!

JIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Combined malonic and methylmalonic aciduria (CMAMMA; OMIM 614265) is a rare disorder of mitochondrial fatty acid synthesis caused by pathogenic variants in the ACSF3 gene, which encodes malonyl‐CoA synthetase. The clinical presentation is highly heterogeneous and may include seizures, memory impairment, psychiatric manifestations, and ...
Khaled Alatibi, Martin J. Hug, Sara Tucci   +2 more
wiley   +1 more source

Ornithine decarboxylase expression in the human and mouse adult prostate.

, 2015
In the adult human prostate, ornithine decarboxylase protein was expressed in the basal and luminal cells of the epithelium (A). The negative control with primary antibody omitted showed no staining (B).
Linnea J. Parkhurst (802439), Rita L. Malinowski (802438), Paul C. Marker (782541), Melissa Gamat (802437), Laura M. Steinke (802440)   +4 more
core   +1 more source

Amino Acid Metabolism in Health and Disease

MedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su, Jinyu Liu, Xiaoliang Deng, Yanqun Luo, Haiping Xue, Lei Wang, Lianjun Xing, Tao Wu   +7 more
wiley   +1 more source

Stabilization of ornithine decarboxylase in erythroleukemia cells depleted of ATP

, 1989
Ornithine decarboxylase activity in Friend erythroleukemia cells decayed with a half-life of 50 minutes after addition of cycloheximide and at a faster rate after addition of spermidine.
Caldarera C. M., Marmiroli S., Guarnieri C., Flamigni F.   +3 more
core   +1 more source

Microbiological, Molecular Diagnosis and Antimicrobial Resistance of Bordetella bronchiseptica in the Equine Reproductive Tract in Brazil

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
First report of Bordetella bronchiseptica in the reproductive tract of Brazilian mares. Uterine lavage samples from mares with endometritis and infertility were positive by culture, PCR (237 bp flaA), sequencing and phylogenetic analysis. Isolates showed multidrug resistance, emphasizing the relevance of this pathogen in equine reproductive disorders ...
Samira Salim Mello Gallo, Maria de Lourdes Amaral Bernardino, Luiz Antonio Silveira da Motta Júnior, Francisco Carlos Rodrigues de Oliveira, Marcos Antonio Pessanha Barreto, Marcio Manhães Folly   +5 more
wiley   +1 more source