Results 61 to 70 of about 21,338 (219)

Current Insight into Human Ornithine Aminotransferase: A Review

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani, Carla Borri Voltattorni, Riccardo Montioli   +2 more
wiley   +1 more source

Inhibition of Ornithine Decarboxylase 1 Mitigates Denervation‐Induced Muscle Atrophy by Suppressing Proteolysis and Preserving Muscle Stem Cell Homeostasis

Cell Proliferation, EarlyView.
Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang, Feifan Chang, Siliang Ge, Fuming Cao, Pincong Fu, Haobo Zhang, Ming Chen, Yi Li, Peifu Tang, Pengbin Yin   +9 more
wiley   +1 more source

Regulation of ovarian ornithine decarboxylase by human chorionic gonadotrophin

, 1987
Treatment of 29-day-old female Sprague-Dawley rats with human chorionic gonadotrophin (hCG) produced a large and rapid increase in the activity of ornithine decarboxylase.
A. E. Pegg, G. J. Sertich, L. Persson
core   +1 more source

The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis

Medical Sciences, 2017
It has been hypothesized that both the 3′-untranslated region (3′UTR) and the 5′-untranslated region (5′UTR) of the ornithine decarboxylase (ODC) mRNA influence the expression of the ODC protein.
Shannon L. Nowotarski, Lisa M. Shantz
doaj   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

A quantitative cytochemical method for ornithine decarboxylase activity.

, 1990
Although decarboxylases, particularly ornithine decarboxylase, are of considerable importance in cell metabolism, it has been impossible to demonstrate their activity histochemically, as this depends on trapping carbon dioxide at neutral pH values.
R A Dodds, G T Frost, A A Pitsillides
core   +1 more source

Thioredoxin system modulates metabolic and stomatal responses to elevated CO2 in Arabidopsis

New Phytologist, EarlyView.
Integrative model of extraplastidial NADPH‐dependent thioredoxin reductase/thioredoxin system‐mediated regulation of stomatal function, redox homeostasis, and metabolic responses under ambient and elevated CO2 in Arabidopsis thaliana. Summary The NADPH‐dependent thioredoxin reductase/thioredoxin (NTR/TRX) system plays a central role in maintaining ...
Paula da Fonseca‐Pereira, Domingos F. Mélo Neto, Rita de Cássia Monteiro‐Batista, Daniel Gomes Coelho, Jaciara Lana‐Costa, Leonardo Perez de Souza, Ina Krahnert, Danilo M. Daloso, Jorge Gago, Alisdair R. Fernie, Wagner L. Araújo, Adriano Nunes‐Nesi   +11 more
wiley   +1 more source

Phosphorylation of ornithine decarboxylase in intact erythroleukemia cells

, 1990
32P-labeled ornithine decarboxylase was isolated by immunoprecipitation from murine erythroleukemia cells incubated in a medium containing [32P]ortophosphoric acid.
Meggio F., Marmiroli S., Guarnieri C., Flamigni F., Pinna L. A.   +4 more
core   +1 more source

Differential effects of difluoromethylornithine on basal and induced activity of cerebral ornithine decarboxylase and mRNA [PDF]

, 1991
The induction of the activity of cerebral ornithine decarboxylase (EC 4.1.1.17) and mRNA by electrical stimulation exhibits regional differences. The effects of the enzyme inhibitor difluoromethylornithine on these regional variations was examined ...
Zawia, NH, Bondy, SC, Mattia, CJ
core   +1 more source

Negative Regulators of Rice Agronomic Traits: Functional Insights and Applications in Genome Editing‐Based Breeding

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rice is the staple crop for more than half of the global population, and improving grain yield, grain quality, and stress resistance remain central goals of modern rice breeding. Among current precision breeding strategies, genome editing has created new opportunities for crop improvement, but its success depends heavily on the selection of ...
Wenhao Wu, Feng Jin, Huaxiang Xu, Ranran Liao, Zhongming Fang   +4 more
wiley   +1 more source