Results 41 to 50 of about 21,397 (220)
Assay of Ornithine Decarboxylase and Spermidine/Spermine N1-acetyltransferase Activities
The polyamines, spermidine (Spd) and spermine, and their diamine precursor putrescine, are important regulators of various cellular functions, such as proliferation and differentiation.
Mervi Hyvönen +2 more
doaj +1 more source
The effect of polyamine biosynthesis inhibitors on the salt stress response of rice seedlings was investigated. For this, DL-α-difluoromethylarginine (DFMA) and DL-α-difluoromethylornithine (DFMO), two competitive inhibitors of arginine decarboxylase ...
A. Yamamoto, I.-S. Shim, S. Fujihara
doaj +1 more source
Dietary Modification of UV-Induced Epidermal Ornithine Decarboxylase [PDF]
The effect of several dietary antioxidant supplements upon ultraviolet light-induced ornithine decarboxylase activity was determined. Hairless mice received diets supplemented with either butylated hydroxytoluene, disulfiram, phenobarbital, glutathione ...
Black, Homer S. +2 more
core +1 more source
Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution. [PDF]
Polyamine biosynthetic pathway is a validated therapeutic target for large number of infectious diseases including cancer, giardiasis and African sleeping sickness, etc.
Preeti +4 more
doaj +1 more source
Post-Transcriptional Suppression of Human Ornithine Decarboxylase Gene Expression by Phorbol Esters in Human Keratinocytes [PDF]
The induction of ornithine decarboxylase levels by the phorbol ester 12-0-tetradecanoyl-phorbol- 13-acetate (TPA) in mouse skin has been shown to be integral to tumor promotion by TPA, and changes in ornithine decarboxylase activity indicate the ...
Rhim, Johng S +4 more
core +1 more source
Nitric oxide (NO) is known to antagonize ethylene by various mechanisms; one of such mechanisms is reducing ethylene levels by competitive action on S-adenosyl-L-methionine (SAM)—a common precursor for both ethylene and polyamines (PAs ...
Veeresh Lokesh +6 more
doaj +1 more source
Difluoromethylornithine (DFMO) and AMXT 1501 inhibit capsule biosynthesis in pneumococci
Polyamines are small cationic molecules that have been linked to various cellular processes including replication, translation, stress response and recently, capsule regulation in Streptococcus pneumoniae (Spn, pneumococcus).
Moses B. Ayoola +7 more
doaj +1 more source
Ornithine decarboxylase expression in the human and mouse adult prostate. [PDF]
In the adult human prostate, ornithine decarboxylase protein was expressed in the basal and luminal cells of the epithelium (A). The negative control with primary antibody omitted showed no staining (B).
Linnea J. Parkhurst (802439) +4 more
core +1 more source
Background Enterobacter aerogenes and Klebsiella pneumoniae are common isolates in clinical microbiology and important as producers of extended spectrum β-lactamases (ESBL). The discrimination between both species, which is routinely based on biochemical
Verschraegen Gerda +6 more
doaj +1 more source
Posttranscriptional Regulation of Ornithine Decarboxylase [PDF]
Activity of the polyamine biosynthetic enzyme ornithine decarboxylase (ODC) and intracellular levels of ODC protein are controlled very tightly. Numerous studies have described ODC regulation at the levels of transcription, translation, and protein degradation in normal cells and dysregulation of these processes in response to oncogenic stimuli ...
Nowotarski, Shannon L. +2 more
openaire +3 more sources

