Multi-Temperature Crystallography of Polyamine Biosynthesis Enzymes Reveals Differing Active Site Conformations at RT than 100K [PDF]
Structural DynamicsThe polyamine biosynthetic pathway synthesizes the polyamines putrescine, spermidine, and spermine from ornithine and S-adenosyl methionine. These polyamines are important molecules in metabolism and are associated with growth and proliferation of cells ...
Jonathan A Clinger
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Determinants of the differential antizyme-binding affinity of ornithine decarboxylase. [PDF]
PLoS ONE, 2011 Ornithine decarboxylase (ODC) is a ubiquitous enzyme that is conserved in all species from bacteria to humans. Mammalian ODC is degraded by the proteasome in a ubiquitin-independent manner by direct binding to the antizyme (AZ).
Yen-Chin Liu +5 more
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Journal of Integrative Agriculture, 2021 The mechanism of melatonin (MT) induced chilling tolerance in harvested cucumber fruit was investigated at commercial maturity. In this study, cucumber fruits were treated with 100 µmol L–1 MT at 4°C and 90% relative humidity for 15 d of storage.
Miilion P MADEBO +4 more
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Regulation of ovarian ornithine decarboxylase by human chorionic gonadotrophin [PDF]
, 1987 Treatment of 29-day-old female Sprague-Dawley rats with human chorionic gonadotrophin (hCG) produced a large and rapid increase in the activity of ornithine decarboxylase.
A. E. Pegg, G. J. Sertich, L. Persson
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Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase
Biomolecules, 2020 The biogenic polyamines, spermine, spermidine (Spd) and putrescine (Put) are present at micro-millimolar concentrations in eukaryotic and prokaryotic cells (many prokaryotes have no spermine), participating in the regulation of cellular proliferation and
Mervi T. Hyvönen +9 more
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A quantitative cytochemical method for ornithine decarboxylase activity. [PDF]
, 1990 Although decarboxylases, particularly ornithine decarboxylase, are of considerable importance in cell metabolism, it has been impossible to demonstrate their activity histochemically, as this depends on trapping carbon dioxide at neutral pH values.
R A Dodds, G T Frost, A A Pitsillides
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Putrescine Biosynthesis Inhibition in Tomato by DFMA and DFMO Treatment
Bio-Protocol, 2016 This protocol can be used to inhibit the biosynthesis of polyamines, specifically putrescine, in tomato plants grown with NH4+ as a solely N source. In general, polyamines are positively charged small metabolites implicated in physiological processes ...
Emma Fernández-Crespo +5 more
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Phosphorylation of ornithine decarboxylase in intact erythroleukemia cells [PDF]
, 1990 32P-labeled ornithine decarboxylase was isolated by immunoprecipitation from murine erythroleukemia cells incubated in a medium containing [32P]ortophosphoric acid.
Meggio F. +4 more
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Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme. [PDF]
PLoS Neglected Tropical Diseases, 2008 BACKGROUND: The polyamines putrescine, spermidine, and spermine are organic cations that are required for cell growth and differentiation. Ornithine decarboxylase (ODC), the first and rate-limiting enzyme in the polyamine biosynthetic pathway, is a ...
Anupam Jhingran +8 more
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In vivo hormonal induction of ornithine decarboxylase in rat kidney [PDF]
, 1976 Single pharmacological doses of parathyroid hormone, calcitonin, vasopressin, d-aldosterone, or L-triiodothyronine produced a significant increase in the ornithine decarboxylase activity of rat kidney.
M. E. Ferioli, G. Scalabrino
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