Results 31 to 40 of about 50,539 (212)

Determinants of the differential antizyme-binding affinity of ornithine decarboxylase. [PDF]

PLoS ONE, 2011
Ornithine decarboxylase (ODC) is a ubiquitous enzyme that is conserved in all species from bacteria to humans. Mammalian ODC is degraded by the proteasome in a ubiquitin-independent manner by direct binding to the antizyme (AZ).
Yen-Chin Liu, Den-Hua Hsu, Chi-Liang Huang, Yi-Liang Liu, Guang-Yaw Liu, Hui-Chih Hung   +5 more
doaj   +1 more source

Melatonin treatment induces chilling tolerance by regulating the contents of polyamine, γ-aminobutyric acid, and proline in cucumber fruit

Journal of Integrative Agriculture, 2021
The mechanism of melatonin (MT) induced chilling tolerance in harvested cucumber fruit was investigated at commercial maturity. In this study, cucumber fruits were treated with 100 µmol L–1 MT at 4°C and 90% relative humidity for 15 d of storage.
Miilion P MADEBO, Si-ming LUO, Li WANG, Yong-hua ZHENG, Peng JIN   +4 more
doaj   +1 more source

Putrescine Biosynthesis Inhibition in Tomato by DFMA and DFMO Treatment

Bio-Protocol, 2016
This protocol can be used to inhibit the biosynthesis of polyamines, specifically putrescine, in tomato plants grown with NH4+ as a solely N source. In general, polyamines are positively charged small metabolites implicated in physiological processes ...
Emma Fernández-Crespo, Ana González-Hernández, Loredana Scalschi, Eugenio Llorens, Pilar García-Agustín, Gemma Camañes   +5 more
doaj   +1 more source

Hydroxylamine Analogue of Agmatine: Magic Bullet for Arginine Decarboxylase

Biomolecules, 2020
The biogenic polyamines, spermine, spermidine (Spd) and putrescine (Put) are present at micro-millimolar concentrations in eukaryotic and prokaryotic cells (many prokaryotes have no spermine), participating in the regulation of cellular proliferation and
Mervi T. Hyvönen, Tuomo A. Keinänen, Gulgina K. Nuraeva, Dmitry V. Yanvarev, Maxim Khomutov, Elena N. Khurs, Sergey N. Kochetkov, Jouko Vepsäläinen, Alexander A. Zhgun, Alex R. Khomutov   +9 more
doaj   +1 more source

Characterization of the Entamoeba histolytica ornithine decarboxylase-like enzyme. [PDF]

PLoS Neglected Tropical Diseases, 2008
BACKGROUND: The polyamines putrescine, spermidine, and spermine are organic cations that are required for cell growth and differentiation. Ornithine decarboxylase (ODC), the first and rate-limiting enzyme in the polyamine biosynthetic pathway, is a ...
Anupam Jhingran, Prasad K Padmanabhan, Sushma Singh, Krishanpal Anamika, Abhijeet A Bakre, Sudha Bhattacharya, Alok Bhattacharya, Narayanaswamy Srinivasan, Rentala Madhubala   +8 more
doaj   +1 more source

Assay of Ornithine Decarboxylase and Spermidine/Spermine N1-acetyltransferase Activities

Bio-Protocol, 2014
The polyamines, spermidine (Spd) and spermine, and their diamine precursor putrescine, are important regulators of various cellular functions, such as proliferation and differentiation.
Mervi Hyvönen, Tuomo Keinänen, Leena Alhonen   +2 more
doaj   +1 more source

Ornithine Decarboxylase in Rat Skin

Journal of Investigative Dermatology, 1978
Ornithine decarboxylase (ODC; E.C.4.1.1.17) activities can be stimulated 2-10 fold in rat epidermis and dermis by hair plucking. Stimulation does not involve the removal of a soluble ODC inhibitor. ODC activity in the dermis and whole skin decreased with aging, while the epidermis showed little change.
Morrison, Deane M., Goldsmith, Lowell A.
openaire   +2 more sources

Inhibition of putrescine biosynthesis enhanced salt stress sensitivity and decreased spermidine content in rice seedlings

Biologia Plantarum, 2017
The effect of polyamine biosynthesis inhibitors on the salt stress response of rice seedlings was investigated. For this, DL-α-difluoromethylarginine (DFMA) and DL-α-difluoromethylornithine (DFMO), two competitive inhibitors of arginine decarboxylase ...
A. Yamamoto, I.-S. Shim, S. Fujihara
doaj   +1 more source

Structural insight into DFMO resistant ornithine decarboxylase from Entamoeba histolytica: an inkling to adaptive evolution. [PDF]

PLoS ONE, 2013
Polyamine biosynthetic pathway is a validated therapeutic target for large number of infectious diseases including cancer, giardiasis and African sleeping sickness, etc.
Preeti, Satya Tapas, Pravindra Kumar, Rentala Madhubala, Shailly Tomar   +4 more
doaj   +1 more source

Difluoromethylornithine (DFMO) and AMXT 1501 inhibit capsule biosynthesis in pneumococci

Scientific Reports, 2022
Polyamines are small cationic molecules that have been linked to various cellular processes including replication, translation, stress response and recently, capsule regulation in Streptococcus pneumoniae (Spn, pneumococcus).
Moses B. Ayoola, Leslie A. Shack, Jung Hwa Lee, Juhyeon Lim, Hyungjin Eoh, Edwin Swiatlo, Otto Phanstiel, Bindu Nanduri   +7 more
doaj   +1 more source