Results 51 to 60 of about 21,338 (219)

Difluoromethylornithine (DFMO) and AMXT 1501 inhibit capsule biosynthesis in pneumococci

Scientific Reports, 2022
Polyamines are small cationic molecules that have been linked to various cellular processes including replication, translation, stress response and recently, capsule regulation in Streptococcus pneumoniae (Spn, pneumococcus).
Moses B. Ayoola, Leslie A. Shack, Jung Hwa Lee, Juhyeon Lim, Hyungjin Eoh, Edwin Swiatlo, Otto Phanstiel, Bindu Nanduri   +7 more
doaj   +1 more source

Posttranscriptional Regulation of Ornithine Decarboxylase [PDF]

, 2011
Activity of the polyamine biosynthetic enzyme ornithine decarboxylase (ODC) and intracellular levels of ODC protein are controlled very tightly. Numerous studies have described ODC regulation at the levels of transcription, translation, and protein degradation in normal cells and dysregulation of these processes in response to oncogenic stimuli ...
Nowotarski, Shannon L., Origanti, Sofia, Shantz, Lisa M.   +2 more
openaire   +3 more sources

Polyamine Induction in Postharvest Banana Fruits in Response to NO Donor SNP Occurs via l-Arginine Mediated Pathway and Not via Competitive Diversion of S-Adenosyl-l-Methionine

Antioxidants, 2019
Nitric oxide (NO) is known to antagonize ethylene by various mechanisms; one of such mechanisms is reducing ethylene levels by competitive action on S-adenosyl-L-methionine (SAM)—a common precursor for both ethylene and polyamines (PAs ...
Veeresh Lokesh, Girigowda Manjunatha, Namratha S. Hegde, Mallesham Bulle, Bijesh Puthusseri, Kapuganti Jagadis Gupta, Bhagyalakshmi Neelwarne   +6 more
doaj   +1 more source

Leishmania donovani: cellular control of ornithine decarboxylase in promastigotes

, 1995
Ornithine decarboxylase, a key enzyme in polyamine biosynthesis, is essential for normal cell growth and proliferation. Furthermore, the inhibition of this enzyme is a potential way of controlling such growth.
Madhubala, R., Mukhopadhyay, Rita
core   +1 more source

Functional roles of the dimer-interface residues in human ornithine decarboxylase. [PDF]

PLoS ONE, 2014
Ornithine decarboxylase (ODC) catalyzes the decarboxylation of ornithine to putrescine and is the rate-limiting enzyme in the polyamine biosynthesis pathway. ODC is a dimeric enzyme, and the active sites of this enzyme reside at the dimer interface. Once
Chien-Yun Lee, Yi-Liang Liu, Chih-Li Lin, Guang-Yaw Liu, Hui-Chih Hung   +4 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Impact and mechanisms of cinnamaldehyde on putrescine production by Obesumbacterium proteus OP216735 during the process of Xinjiang sausage

Food Science and Human Wellness
This study investigated the effects of cinnamaldehyde on putrescine production by Obesumbacterium proteus in pure cultures and Xinjiang sausage. Scanning electron microscopy was used to analyze the cell morphology of the test bacteria, and reverse ...
Honghong Yu, Shiyi Zhu, Shiling Lu
doaj   +1 more source

Monitoring and Mitigation Strategies for Hazardous Compounds in Chinese Rice Wine (Huangjiu): A Comprehensive Review

Food Safety and Health, EarlyView.
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu, Zhiqiang Kong, Lin Li, Yifan Zhang, Bei Fan, Minmin Li   +5 more
wiley   +1 more source

Macronutrient and micronutrient profiles of meat types: insights into human health and diet

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş, Serap Göncü, Fatma Hepsağ, Nazan Koluman, Yesim Ozogul   +4 more
wiley   +1 more source

Human Decidual Mesenchymal Stem Cells Obtained From Early Pregnancy Improve Cardiac Revascularization Postinfarction by Activating Ornithine Metabolism

Frontiers in Cardiovascular Medicine, 2022
BackgroundCompared with bone marrow mesenchymal stem cells (BMSCs), decidual mesenchymal stem cells (DMSCs) are easy to obtain and exhibit excellent angiogenic effects, but their role in cell transplantation after myocardial infarction (MI) remains ...
Kegong Chen, Kegong Chen, Kegong Chen, Long Bai, Long Bai, Long Bai, Jingtong Lu, Jingtong Lu, Jingtong Lu, Wei Chen, Wei Chen, Chang Liu, Erliang Guo, Erliang Guo, Erliang Guo, Xionghai Qin, Xionghai Qin, Xuan Jiao, Xuan Jiao, Mingli Huang, Mingli Huang, Hai Tian, Hai Tian   +22 more
doaj   +1 more source